Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | STAMBP | O95630 | 1/20 | 0.50 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905578 | 0.86 | RAB9A (0.64) | RAB9ANPC1L3MBTL1TDP1PSMD14 | |
| SCHEMBL1901528 | 0.85 | TDP1 (0.68) | RAB9ANPC1TDP1PKMMLYCD | |
| SCHEMBL18905575 | 0.82 | TDP1 (0.74) | RAB9ANPC1L3MBTL1TDP1PKM | |
| SCHEMBL18905577 | 0.80 | RAB9A (0.64) | RAB9ANPC1L3MBTL1TDP1PKM | |
| SCHEMBL31344217 | 0.80 | RAB9A (0.64) | RAB9ANPC1L3MBTL1TDP1MLYCD | |
| SCHEMBL18905580 | 0.76 | RAB9A (0.76) | RAB9ANPC1L3MBTL1TDP1PSMD14 | |
| SCHEMBL11895627 | 0.76 | RAB9A (0.58) | RAB9ANPC1L3MBTL1TDP1PKM | |
| SCHEMBL2118595 | 0.75 | HDAC2 (0.69) | RAB9ANPC1MLYCDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1867782 | 0.74 | RAB9A (0.60) | RAB9ANPC1L3MBTL1TDP1PKM | |
| SCHEMBL3982160 | 0.73 | ALDH1A1 (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |