Methacrylic Acid

Methacrylic Acid

SCHEMBL4364078

C=C(C)C(=O)O.CC(C)CC(C)(C)C

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TET2 Q6N021 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MMP8 P22894 1/20 0.32
TGFBR1 P36897 1/20 0.31
GRM2 Q14416 1/20 0.31
GRM3 Q14832 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28048717 0.85 ALDH1A1 (0.39) TDP1ALDH1A1MMP8GRM2GRM3
Acetone SCHEMBL9097300 0.83 ALDH1A1 (0.41) TSHRTDP1ALDH1A1MMP8GRM2
SCHEMBL10425017 0.83 TSHR (0.31) TSHR
Bicarbonate SCHEMBL5085250 0.83 MMP8 (0.36) TDP1ALDH1A1MMP8GRM2GRM3
SCHEMBL7194359 0.83 TSHR (0.31) TSHR
Acetic Acid SCHEMBL18429380 0.81 ALDH1A1 (0.36) TDP1ALDH1A1MMP8GRM2GRM3
Methacrylic Acid SCHEMBL8956104 0.81 TSHR (0.35) TSHRTET2TDP1ALDH1A1CYP2C19
Hydrogen Peroxide SCHEMBL28073128 0.80 TSHR (0.35) TSHRMMP8GRM2GRM3
Methacrylic Acid SCHEMBL20573604 0.78 TSHR (0.36) TSHRTDP1ALDH1A1TGFBR1CYP2C19
SCHEMBL6139393 0.78 RNPEP (0.37) ALDH1A1MMP8GRM2GRM3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619040-B2 Compositions containing copolymers of olefinic monomers PPG INDUSTRIES OHIO, INC. (US) 2009-11-17 US disclosed
WO-2006116363-A1 COMPOSITIONS CONTAINING COPOLYMERS OF OLEFINIC MONOMERS PPG INDUSTRIES OHIO, INC. (US) 2006-11-02 WO disclosed
US-20050250911-A1 Compositions containing copolymers of olefinic monomers PPG INDUSTRIES OHIO, INC. 2005-11-10 US disclosed
US-20040143079-A1 Compositions containing copolymers of isobutylene type monomers PPG INSUSTRIES OHIO, INC. 2004-07-22 US disclosed
WO-2003070795-A1 COPOLYMERS COMPRISING ISOBUTYLENE TYPE AND ACRYLATE TYPE MONOMERS PPG INDUSTRIES OHIO, INC. (US) 2003-08-28 WO disclosed