SCHEMBL4364091

SCHEMBL4364091

CC(=NN=C(C)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FURIN P09958 2/20 0.61
ESR1 P03372 6/20 0.50
LMNA P02545 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ESR2 Q92731 4/20 0.50
POLB P06746 1/20 0.50
HSD17B1 P14061 1/20 0.46
MAPT P10636 5/20 0.46
HSD17B10 Q99714 4/20 0.46
CYP3A4 P08684 3/20 0.46
ALOX15 P16050 3/20 0.46
HIF1A Q16665 3/20 0.46
NR3C1 P04150 2/20 0.46
TP53 P04637 2/20 0.46
CYP1A2 P05177 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12260084 1.00 FURIN (0.61) FURINESR1LMNAMEN1KMT2A
SCHEMBL29293222 0.91 ACHE (0.59) FURINESR1LMNAMEN1KMT2A
SCHEMBL14626976 0.81 ESR1 (0.48) ESR1LMNAMEN1KMT2AESR2
SCHEMBL17548938 0.81 ESR1 (0.48) ESR1LMNAMEN1KMT2AESR2
SCHEMBL467701 0.81 ESR1 (0.48) ESR1LMNAMEN1KMT2AESR2
SCHEMBL2704783 0.79 MEN1 (0.47) FURINESR1LMNAMEN1KMT2A
SCHEMBL10802341 0.78 FURIN (0.61) FURINLMNAMEN1KMT2APOLB
SCHEMBL9349552 0.77 ESR2 (0.60) ESR1LMNAMEN1KMT2AESR2
SCHEMBL12304824 0.76 FURIN (0.65) FURINESR1LMNAMEN1KMT2A
SCHEMBL2682212 0.76 FURIN (0.58) FURINLMNAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948864-A BLENDS ACUSHNET COMPANY (US) 1999-09-07 US claimed
WO-2017066929-A1 MODIFIED EPOXY RESIN AND CURABLE RESIN COMPOSITION COMPRISING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-04-27 WO disclosed
US-7540991-B2 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. (JP) 2009-06-02 US disclosed
EP-1615286-B1 Ion conductive polymer electrolyte membrane and production method for the same POLYMATECH CO LTD (JP) 2007-09-12 EP disclosed
EP-1615286-A1 Ion conductive polymer electrolyte membrane and production method for the same Polymatech Co., Ltd. (JP) 2006-01-11 EP disclosed
US-20060004112-A1 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. 2006-01-05 US disclosed
US-5948864-A BLENDS ACUSHNET COMPANY (US) 1999-09-07 US disclosed
EP-0674683-B1 POLYMERIC BLENDS RAYCHEM CORP (US) 1997-10-15 EP disclosed
EP-0674683-A1 POLYMERIC BLENDS. RAYCHEM CORP (US) 1995-10-04 EP disclosed
EP-0348666-B1 Anisotropic melt-forming polycarbonates and method for making GEN ELECTRIC (US) 1995-01-18 EP disclosed
WO-1994014890-A1 POLYMERIC BLENDS RAYCHEM CORPORATION (US) 1994-07-07 WO disclosed
EP-0348666-A2 Anisotropic melt-forming polycarbonates and method for making GENERAL ELECTRIC COMPANY (US) 1990-01-03 EP disclosed