SCHEMBL17548938

SCHEMBL17548938

C/C(=N/O)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.48
ESR2 Q92731 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
CA9 Q16790 4/20 0.46
HSD17B1 P14061 1/20 0.44
LMNA P02545 4/20 0.44
CYP3A4 P08684 4/20 0.44
MAPT P10636 4/20 0.44
CYP1A2 P05177 3/20 0.44
CYP2C19 P33261 3/20 0.44
ALOX15 P16050 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 3/20 0.44
GAA P10253 2/20 0.44
NR3C1 P04150 2/20 0.44
TP53 P04637 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467701 1.00 ESR1 (0.48) ESR1ESR2MEN1KMT2ACA9
SCHEMBL14626976 1.00 ESR1 (0.48) ESR1ESR2MEN1KMT2ACA9
SCHEMBL14298196 0.89 CA9 (0.52) MEN1KMT2ACA9LMNACYP3A4
SCHEMBL12360950 0.89 CA9 (0.52) MEN1KMT2ACA9LMNACYP3A4
SCHEMBL12260084 0.81 FURIN (0.61) ESR1ESR2MEN1KMT2ACA9
SCHEMBL13645704 0.81 CA9 (0.47) ESR1ESR2KMT2ACA9HSD17B1
SCHEMBL4364091 0.81 FURIN (0.61) ESR1ESR2MEN1KMT2ACA9
SCHEMBL12741076 0.79 CA9 (0.56) CA9LMNACYP3A4MAPTCYP1A2
SCHEMBL514858 0.79 CA9 (0.56) CA9LMNACYP3A4MAPTCYP1A2
SCHEMBL514859 0.79 CA9 (0.56) CA9LMNACYP3A4MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 EP disclosed
US-10286504-B2 Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-05-14 US disclosed
US-10014474-B2 Composition for forming gate insulating film, organic thin film transistor, electronic paper, and display device FUJIFILM CORPORATION (JP) 2018-07-03 US disclosed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10014474-B2 Composition for forming gate insulating film, organic thin film transistor, electronic paper, and display device TEC, EPCAM, MIF ESR1 2822/4885ESR2 4557/4885MEN1 970/4885
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 ESR1 3208/4885ESR2 863/4885MEN1 2008/4885
US-10286504-B2 Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide HPD, HMBS, NAT1 ESR1 4147/4885ESR2 4190/4885MEN1 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.