Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366868 | 0.95 | SLC8A1 (0.50) | SLC8A1 | |
| SCHEMBL4370450 | 0.90 | SLC8A1 (0.49) | SLC8A1 | |
| SCHEMBL4370735 | 0.89 | KDM4E (0.57) | SLC8A1 | |
| SCHEMBL4366657 | 0.88 | ESR1 (0.51) | SLC8A1 | |
| SCHEMBL4360457 | 0.88 | SLC8A1 (0.58) | SLC8A1 | |
| SCHEMBL4364059 | 0.87 | SLC8A1 (0.51) | SLC8A1 | |
| SCHEMBL4374275 | 0.87 | SLC8A1 (0.47) | SLC8A1 | |
| SCHEMBL4363486 | 0.86 | SLC8A1 (0.43) | SLC8A1 | |
| SCHEMBL4366043 | 0.84 | SLC8A1 (0.43) | SLC8A1 | |
| SCHEMBL4363592 | 0.83 | SLC8A1 (0.44) | SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482340-B2 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system | ORION CORPORATION (FI) | 2009-01-27 | — | — | US | disclosed |
| US-20060241147-A1 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system | ORION CORPORATION (FI) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241147-A1 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system | SLC8B1, CACNA1A, MCU | SLC8A1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.