SCHEMBL4364368

SCHEMBL4364368

Nc1ccc(N(N=O)N=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.46
ALDH1A1 P00352 7/20 0.46
CYP3A4 P08684 6/20 0.46
ALOX15 P16050 4/20 0.46
MAPK1 P28482 3/20 0.46
TP53 P04637 2/20 0.46
MAPT P10636 5/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
CYP2C9 P11712 2/20 0.42
KDM4E B2RXH2 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
TSHR P16473 3/20 0.41
PSMD14 O00487 1/20 0.41
RECQL P46063 1/20 0.41
GFER P55789 1/20 0.41
RAB9A P51151 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691984 0.75 ALDH1A1 (0.54) TDP1ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL11370021 0.75 ALDH1A1 (0.42) TDP1ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL1447155 0.72 ALDH1A1 (0.62) TDP1ALDH1A1CYP3A4ALOX15MAPT
SCHEMBL21371702 0.69 ALDH1A1 (0.54) TDP1ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL2009254 0.67 TDP1 (0.78) TDP1ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL308803 0.67 TDP1 (0.78) TDP1ALDH1A1CYP3A4ALOX15MAPK1
Nitrous Acid SCHEMBL9786412 0.65 MEN1 (0.53) TDP1ALDH1A1CYP3A4ALOX15MAPK1
SCHEMBL9149010 0.65 CYP3A4 (0.55) TDP1ALDH1A1CYP3A4ALOX15MAPK1
Hydrochloric Acid SCHEMBL9238428 0.65 CYP3A4 (0.74) TDP1ALDH1A1CYP3A4ALOX15MAPK1
Hydrochloric Acid SCHEMBL31558767 0.65 CYP3A4 (0.74) TDP1ALDH1A1CYP3A4ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118236541-A Hydrogel dressing for accelerating wound healing of diabetes mellitus as well as preparation method and application thereof 四川大学 2024-06-25 CN claimed
CN-114652831-B Near infrared II region controlled release nitric oxide nano carrier material and preparation method and application thereof 暨南大学 2023-11-03 CN claimed
CN-115125669-B Ultrasonic-responsive nitric oxide-releasing electrospun membrane and preparation method thereof 华中科技大学同济医学院附属协和医院 2023-08-11 CN claimed
CN-116099001-B PP-Mo-NO photo-thermal antibacterial agent and preparation method and application thereof 潍坊医学院附属医院 2023-06-16 CN claimed
CN-116099001-A PP-Mo-NO photo-thermal antibacterial agent and preparation method and application thereof 潍坊医学院附属医院 2023-05-12 CN claimed
CN-114106354-B Nanocomposite capable of in-situ autocatalytic generation of hydrogen peroxide and sustained release of NO and free radicals, and preparation method and application thereof 暨南大学 2023-04-11 CN claimed
CN-115125669-A Ultrasonic-responsive nitric oxide-releasing electrospun membrane and preparation method thereof 华中科技大学同济医学院附属协和医院 2022-09-30 CN claimed
CN-114652831-A Near-infrared II-region controlled-release nitric oxide nano carrier material and preparation method and application thereof 暨南大学 2022-06-24 CN claimed
CN-114106354-A Nanocomposite capable of in-situ autocatalytic generation of hydrogen peroxide and sustained release of NO and free radicals, and preparation method and application thereof 暨南大学 2022-03-01 CN claimed
CN-110960724-B Medicinal hydrogel and preparation method thereof 暨南大学 2022-02-15 CN claimed
CN-111171332-B Nitric oxide releasing hydrogel and preparation method thereof 广州贝奥吉因生物科技股份有限公司 2021-09-28 CN claimed
CN-113425740-A Methods for enhancing blood brain barrier permeability 浦项工科大学校产学协力团 2021-09-24 CN claimed
CN-111171332-A Nitric oxide releasing hydrogel and preparation method thereof 广州贝奥吉因生物科技股份有限公司 2020-05-19 CN claimed
CN-110960724-A Medicinal hydrogel and preparation method thereof 暨南大学 2020-04-07 CN claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
JP-5194614-A None JP disclosed
CN-117815438-B Multifunctional hydrogel and preparation method and application thereof 中南大学湘雅医院 2024-07-12 CN disclosed
WO-2006097350-A1 ANHYDROUS COSMETIC COMPOSITION CONTAINING AN AGENT FOR PROMOTING THE MICROCIRCULATION AND A POLYOL, USES THEREOF L'OREAL (FR) 2006-09-21 WO disclosed
US-7029556-B1 Method for purifying (meth)acrylic monomers by distillation ARKEMA (FR) 2006-04-18 US disclosed
JP-H05194614-A COMPOSITION FOR INHIBITING ADDITION POLYMERIZATION OF ACRYLIC ACID AND ESTER THEREOF UNIROYAL CHEM CO INC 1993-08-03 JP disclosed