Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365307 | 0.97 | KCNJ1 (0.44) | KCNJ1KCNH2RAB9ASMN1; SMN2PTGES | |
| SCHEMBL12342820 | 0.92 | KCNJ1 (0.44) | KCNJ1KCNH2RAB9ASMN1; SMN2CHRM5 | |
| SCHEMBL12342822 | 0.89 | KCNJ1 (0.43) | KCNJ1KCNH2RAB9ASMN1; SMN2CHRM5 | |
| SCHEMBL4360231 | 0.89 | KCNJ1 (0.41) | KCNJ1KCNH2SMN1; SMN2PTGESALOX5 | |
| SCHEMBL4361540 | 0.85 | KCNJ1 (0.40) | KCNJ1KCNH2SMN1; SMN2PTGESALOX5 | |
| SCHEMBL4374792 | 0.82 | BACE1 (0.38) | SMN1; SMN2ALDH1A1KMT2AMEN1SIGMAR1 | |
| SCHEMBL4360997 | 0.80 | BACE1 (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1SIGMAR1 | |
| SCHEMBL4359522 | 0.80 | BACE1 (0.39) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL14546793 | 0.78 | BACE1 (0.39) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL21448731 | 0.77 | KCNJ1 (0.44) | KCNJ1KCNH2RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268810-B2 | Lipophilic chelates and their use in imaging | GUERBET (FR) | 2012-09-18 | — | — | US | disclosed |
| US-20090214441-A1 | Lipophilic Chelates and Their Use in Imaging | GUERBET (FR) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214441-A1 | Lipophilic Chelates and Their Use in Imaging | SLC40A1, TSPO, SLC47A2 | KCNJ1 693/4885KCNH2 1135/4885RAB9A 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.