Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860014 | 0.84 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL467440 | 0.82 | ALDH1A1 (0.33) | TSHRHPGDALDH1A1HCAR2 | |
| Methacrylic Acid SCHEMBL28181106 | 0.82 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL16754766 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TP53 | |
| SCHEMBL29102695 | 0.81 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL719063 | 0.81 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9696417 | 0.81 | TSHR (0.33) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL8899313 | 0.79 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL222966 | 0.79 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL8547396 | 0.79 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521173-B2 | Extrudable antistatic tielayers | EASTMAN KODAK COMPANY (US) | 2009-04-21 | — | — | US | claimed |
| US-20080220353-A1 | EXTRUDABLE ANTISTATIC TIELAYERS | ENCINA PRIVATE CREDIT SPV 2, LLC, AS COLLATERAL AGENT | 2008-09-11 | — | — | US | claimed |
| US-7521173-B2 | Extrudable antistatic tielayers | EASTMAN KODAK COMPANY (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080220353-A1 | EXTRUDABLE ANTISTATIC TIELAYERS | ENCINA PRIVATE CREDIT SPV 2, LLC, AS COLLATERAL AGENT | 2008-09-11 | — | — | US | disclosed |