Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745942 | 1.00 | CTSK (0.58) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL9993970 | 1.00 | CTSK (0.58) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL4366638 | 1.00 | CTSK (0.58) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL19063792 | 1.00 | CTSK (0.58) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL7504577 | 0.91 | CTSK (0.60) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL15317930 | 0.91 | CTSK (0.60) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL12067915 | 0.91 | CTSK (0.60) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL21522663 | 0.89 | CTSK (0.60) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL29268593 | 0.89 | CTSK (0.60) | CTSKALDH1A1GAACPB1CTSL | |
| SCHEMBL19816607 | 0.89 | CTSK (0.52) | CTSKALDH1A1GAACPB1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291940-A1 | AMINOPYRROLIDINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-2003131-A1 | AMINOPYRROLIDINE COMPOUND | Taisho Pharmaceutical Co. Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291940-A1 | AMINOPYRROLIDINE COMPOUND | MC4R, MC5R, MC2R | CTSK 4712/4885ALDH1A1 2275/4885GAA 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.