SCHEMBL4365403

SCHEMBL4365403

CCN(CC)C1(C(NC(=O)c2ccc(Cl)c3ccccc23)c2ccccc2)CCCC1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 11/20 0.39
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35
FFAR1 O14842 1/20 0.33
MAPK1 P28482 1/20 0.33
GPR139 Q6DWJ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4359374 0.89 SLC6A9 (0.41) SLC6A9LMNATSHRKMT2AATM
SCHEMBL3236771 0.83 SLC6A9 (0.53) SLC6A9
SCHEMBL3245146 0.78 SLC6A9 (0.58) SLC6A9
SCHEMBL3232944 0.77 SLC6A9 (0.60) SLC6A9
SCHEMBL4356991 0.77 SCN9A (0.49) SLC6A9LMNAKMT2A
SCHEMBL4355261 0.77 CXCR5 (0.44) SLC6A9LMNAKMT2A
SCHEMBL4355395 0.77 SLC6A9 (0.44) SLC6A9KMT2AATM
SCHEMBL4358870 0.76 TACR3 (0.43) LMNA
SCHEMBL4357362 0.74 PLK1 (0.50) SLC6A9LMNATSHRKMT2A
SCHEMBL3244199 0.74 MEN1 (0.49) SLC6A9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090286828-A1 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES GLAXO GROUP LIMITED (GB) 2009-11-19 US disclosed
US-20090286828-A1 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES GLAXO GROUP LIMITED (GB) 2009-11-19 US disclosed
US-20090286828-A1 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES GLAXO GROUP LIMITED (GB) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286828-A1 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES PNMT, SLC18A2, COMT SLC6A9 1038/4885LMNA 4046/4885TSHR 4054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.