SCHEMBL436562

SCHEMBL436562

CC(=O)O[C@H]1CCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435813 1.00
SCHEMBL6181576 1.00
Hydrochloric Acid SCHEMBL27799701 0.98 CHRM2 (0.37)
Hydrochloric Acid SCHEMBL27702575 0.98 CHRM2 (0.37)
SCHEMBL1489698 0.88 SLC6A1 (0.44)
SCHEMBL21003949 0.88 SLC6A1 (0.44)
Trifluoroacetic Acid SCHEMBL20576082 0.88 SLC6A1 (0.33)
SCHEMBL5640241 0.86 CHRM2 (0.40)
SCHEMBL1490076 0.86 GABRA1 (0.41)
Hydrochloric Acid SCHEMBL27675051 0.86 SLC6A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101028-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE, LTD. (KY) 2025-03-27 US disclosed
EP-4499639-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BeiGene, Ltd. (KY) 2025-02-05 EP disclosed
WO-2023179703-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-09-28 WO disclosed
WO-2020123277-A1 PROTEIN KINASE INHIBITOR PRODRUGS Princeton Drug Discovery Inc. (US) 2020-06-18 WO disclosed
US-9580416-B2 Inhibitors of Bruton's tyrosine kinase PHARMACYCLICS LLC (US) 2017-02-28 US disclosed
US-9580416-B2 Inhibitors of Bruton's tyrosine kinase PHARMACYCLICS LLC (US) 2017-02-28 US disclosed
WO-2016004272-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE PHARMACYCLICS LLC (US) 2016-01-07 WO disclosed
US-20160002225-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE SCHRODINGER, LLC 2016-01-07 US disclosed
US-20160002225-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE SCHRODINGER, LLC 2016-01-07 US disclosed
EP-1562925-A1 PHENYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES Merck & Co., Inc. (US) 2005-08-17 EP disclosed
WO-2004043940-A1 PHENYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES MERCK & CO., INC. (US) 2004-05-27 WO disclosed
EP-0381984-B1 3- or 4-substituted oxotremorine derivatives AMERICAN CYANAMID CO (US) 1995-04-19 EP disclosed
US-5089518-A 3- or 4-substituted oxotremorine derivatives and a method of treating cholinergic dysfunction therewith AMERICAN CYANAMID COMPANY (US) 1992-02-18 US disclosed
US-4952600-A TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM AMERICAN CYANAMID COMPANY (US) 1990-08-28 US disclosed
EP-0381984-A1 3- or 4-substituted oxotremorine derivatives AMERICAN CYANAMID COMPANY (US) 1990-08-16 EP disclosed
US-4937235-A Anticholinergic agents AMERICAN CYANAMID COMPANY (US) 1990-06-26 US disclosed