SCHEMBL436586

SCHEMBL436586

COc1ccc(C(=O)O)cc1N

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.76
LMNA P02545 3/20 0.76
ALDH1A1 P00352 2/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
CA12 O43570 1/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
CA4 P22748 1/20 0.69
CA6 P23280 1/20 0.69
CA7 P43166 1/20 0.69
TPMT P51580 1/20 0.69
CA9 Q16790 1/20 0.69
CA14 Q9ULX7 1/20 0.69
TUBB4A P04350 1/20 0.63
TUBB P07437 1/20 0.63
TUBA3C P0DPH7 1/20 0.63
TUBA1B P68363 1/20 0.63
TUBA4A P68366 1/20 0.63
TUBB4B P68371 1/20 0.63
TUBB3 Q13509 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10434407 0.92 HTT (0.65) HTTLMNAALDH1A1L3MBTL1CA12
SCHEMBL16378685 0.88 CA12 (0.64) HTTLMNAALDH1A1L3MBTL1CA12
SCHEMBL30816922 0.87 HTT (0.59) HTTLMNAALDH1A1L3MBTL1CA12
SCHEMBL310457 0.86 ALDH1A1 (1.00) HTTLMNAALDH1A1L3MBTL1TUBB4A
SCHEMBL16378686 0.85 TTR (0.61) HTTLMNAALDH1A1L3MBTL1CA12
SCHEMBL72751 0.85 CA12 (0.69) HTTLMNAALDH1A1L3MBTL1CA12
SCHEMBL30217617 0.85 ALDH1A1 (0.76) HTTLMNAALDH1A1L3MBTL1CA12
SCHEMBL3124632 0.85 ALDH1A1 (0.76) HTTLMNAALDH1A1L3MBTL1TUBB4A
SCHEMBL761126 0.85 ALDH1A1 (0.76) HTTLMNAALDH1A1L3MBTL1CA12
Hydrochloric Acid SCHEMBL11427585 0.83 ALDH1A1 (0.73) HTTLMNAALDH1A1L3MBTL1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 845 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119770419-A Modified recombinant III type collagen hydrogel loaded with houttuynia cordata vesicles and application thereof 常州大学 2025-04-08 CN claimed
US-12264219-B2 Conductive benzoic acid based polymer containing biomaterial for enhancement of tissue conduction in vitro and in vivo UNIVERSITY HEALTH NETWORK (CA) 2025-04-01 US claimed
CN-119488630-A Injectable piezoelectric conductive hydrogel and preparation method and application thereof 中国科学院长春应用化学研究所 2025-02-21 CN claimed
CN-119345158-A Sulfur ketal bond modified 17-type collagen dopamine drug-loaded nanoparticle composite microneedle patch, and preparation method and application thereof 常州大学 2025-01-24 CN claimed
CN-119157823-A Injectable nano composite hydrogel, preparation method and application thereof 上海市第一人民医院 2024-12-20 CN claimed
CN-119015206-A ROS/pH dual-response modified seventeen-type collagen microneedle patch loaded with bioactive substances and application thereof 常州大学 2024-11-26 CN claimed
EP-3658625-B1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIV HEALTH NETWORK (CA) 2024-06-12 EP claimed
US-20210087336-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIVERSITY HEALTH NETWORK (CA) 2021-03-25 US claimed
EP-3658625-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO University Health Network (CA) 2020-06-03 EP claimed
CN-110997810-A Electrically conductive biomaterials comprising benzoic acid based polymers for enhancing tissue conductivity in vitro and in vivo 大学健康网络 2020-04-10 CN claimed
WO-2003059937-A2 SYNTHETIC ION CHANNELS WASHINGTON UNIVERSITY (US) 2003-07-24 WO claimed
US-5866608-A AROMATIC COMPOUNDS BIORESEARCH, INC. (US) 1999-02-02 US claimed
EP-0429614-B1 AZOPHENYL COMPOUNDS JAMES ROBINSON LTD (GB) 1995-10-11 EP claimed
US-5391699-A Containing an aromatic amine carboxylate, heat resistance BRIDGESTONE CORPORATION (JP) 1995-02-21 US claimed
EP-0571095-A2 Polyester copolymer and process for the production of the same BRIDGESTONE CORPORATION (JP) 1993-11-24 EP claimed
EP-0429614-A1 AZOPHENYL COMPOUNDS. JAMES ROBINSON LTD (GB) 1991-06-05 EP claimed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO claimed
US-4356277-A Reaction products of a polyglycidyl ether of a polyphenol and an amino acid and aqueous solubilized products therefrom PPG INDUSTRIES, INC. (US) 1982-10-26 US claimed
US-4299747-A LININGS PPG INDUSTRIES, INC. (US) 1981-11-10 US claimed
US-3941768-A One step diazotization coupling process CIBA-GEIGY AG (CH) 1976-03-02 US claimed