Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.63 |
| ▸ | TUBB | P07437 | 1/20 | 0.63 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.63 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.63 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.63 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.63 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.63 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.63 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.63 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.63 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.63 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.63 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.63 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310457 | 0.86 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL761126 | 0.85 | ALDH1A1 (0.76) | ALDH1A1LMNAHTTL3MBTL1CREBBP | |
| SCHEMBL30217617 | 0.85 | ALDH1A1 (0.76) | ALDH1A1LMNAHTTL3MBTL1CREBBP | |
| SCHEMBL220432 | 0.85 | LMNA (0.55) | ALDH1A1LMNAHTTL3MBTL1CREBBP | |
| SCHEMBL436586 | 0.85 | HTT (0.76) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL24750205 | 0.83 | MAPT (0.59) | ALDH1A1LMNAHTTL3MBTL1CREBBP | |
| Hydrochloric Acid SCHEMBL11427585 | 0.83 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTL3MBTL1CREBBP | |
| SCHEMBL18093627 | 0.83 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTL3MBTL1CREBBP | |
| SCHEMBL51894 | 0.83 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL8302036 | 0.83 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTL3MBTL1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106837027-B | One kind is anti-to lose hood support rod | 安徽恒天生态农业有限公司 | 2019-01-01 | — | — | CN | claimed |
| CN-114436876-B | Continuous synthesis method of 2-amino-4-acetamino anisole | 中国科学院大连化学物理研究所 | 2023-03-14 | — | — | CN | disclosed |
| CN-114436876-A | Continuous synthesis method of 2-amino-4-acetamino anisole | 中国科学院大连化学物理研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-107673976-B | The Novel synthesis technology of 2- amino -4- acetamido methyl phenyl ethers anisole | 安徽奥瑞化工有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-106278926-B | The method that bianry alloy catalyzes and synthesizes 3- amino-4-methoxyacetanilide | 江苏大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-107286042-A | The preparation method of 2- nitro -4- acetyl-anisidines | 烟台安诺其纺织材料有限公司 | 2017-10-24 | — | — | CN | disclosed |
| US-20100160335-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. | 2010-06-24 | — | — | US | disclosed |
| US-20100160335-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. | 2010-06-24 | — | — | US | disclosed |
| US-20100160335-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. | 2010-06-24 | — | — | US | disclosed |
| EP-2168959-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168959-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-3992537-A | CNS DEPRESSANTS, NEUROLEPTICS, ANTICHOLESTEREMICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-16 | — | — | US | disclosed |
| US-3937708-A | CNS-DEPRESSANTS, NEUROLEPTICS, ANALGESICS, ANTIPHLOGISTICS, SPASMOLYTICS, BRONCHOLYTICS, HYPOTENSIVES, ANTICHOLESTEREMICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160335-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | PDE3A, PDE5A, PDE2A | ALDH1A1 197/4885LMNA 1091/4885HTT 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.