Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ITGAM | P11215 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19041276 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ARAB9ASIGMAR1 | |
| SCHEMBL27757924 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL2172891 | 0.76 | RAB9A (0.41) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8975430 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL29522795 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL5537868 | 0.75 | NOTUM (0.50) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL9217182 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL28674863 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL94509 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL27570415 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1MEN1KMT2ASIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2075289-B1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | OREAL (FR) | 2012-08-15 | — | — | EP | disclosed |
| EP-2075289-B1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | OREAL (FR) | 2012-08-15 | — | — | EP | disclosed |
| EP-2075289-A1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |
| EP-2075289-A1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |
| EP-2075289-A1 | Styryl tetrahydroquinolinium thiol/disulfide compound, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |