Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.47 |
| ▸ | GABRD | O14764 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.47 |
| ▸ | GABRE | P78334 | 3/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.47 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437086 | 0.85 | KDM4E (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL732403 | 0.84 | DHODH (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL437001 | 0.82 | NPC1 (0.55) | KDM4EKMT2AMEN1 | |
| SCHEMBL436954 | 0.82 | HAVCR2 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL439044 | 0.79 | HAVCR2 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL435828 | 0.78 | ACHE (0.39) | KDM4EKMT2AHPGDPARP4 | |
| SCHEMBL436971 | 0.77 | HAVCR2 (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24532133 | 0.76 | KDM4E (0.46) | KDM4EKMT2ADHODHEPRS1MEN1 | |
| SCHEMBL29681293 | 0.76 | KDM4E (0.46) | KDM4EKMT2ADHODHEPRS1MEN1 | |
| SCHEMBL436434 | 0.76 | HAVCR2 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |