Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436945 | 0.86 | KDM4E (0.45) | DYRK1AKMT2AHTTUHRF1PARP1 | |
| SCHEMBL441685 | 0.83 | ACHE (0.35) | ACHEGRIN1GRIN2ABCHEDYRK1A | |
| SCHEMBL439801 | 0.83 | ACHE (0.37) | ACHEGRIN1GRIN2ABCHEDYRK1A | |
| SCHEMBL436591 | 0.78 | GABRP (0.47) | KMT2APARP4KDM4EHPGD | |
| SCHEMBL438361 | 0.76 | ALDH1A1 (0.36) | ACHEGRIN1GRIN2ABCHEDYRK1A | |
| SCHEMBL436601 | 0.76 | KMT2A (0.33) | ACHEGRIN1GRIN2ABCHEDYRK1A | |
| SCHEMBL441701 | 0.75 | ALDH1A1 (0.43) | KMT2AHTTPARP1KDM4EALDH1A1 | |
| SCHEMBL22715874 | 0.73 | PDE5A (0.44) | DYRK1ANQO2HTTPARP1PARP2 | |
| SCHEMBL437001 | 0.73 | NPC1 (0.55) | KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL442160 | 0.71 | NR4A2 (0.40) | NQO2KMT2AUHRF1PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |