Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413462 | 0.86 | KMT2A (0.45) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL10580310 | 0.83 | KMT2A (0.47) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL11769972 | 0.83 | KMT2A (0.47) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL10580850 | 0.80 | KDM4E (0.47) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL3421548 | 0.78 | KMT2A (0.54) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL4366146 | 0.78 | KMT2A (0.54) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL10433550 | 0.78 | KMT2A (0.54) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL9923797 | 0.77 | THRB (0.46) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL13617544 | 0.76 | KMT2A (0.40) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL20050271 | 0.73 | MAOA (0.31) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248919-A1 | Fluorinated trienes and their use as rxr modulators | ELI LILLY AND COMPANY | 2004-12-09 | — | — | US | claimed |
| EP-1368296-A1 | FLUORINATED TRIENES AND THEIR USE AS RXR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-10 | — | — | EP | claimed |
| WO-2002072528-A1 | FLUORINATED TRIENES AND THEIR USE AS RXR MODULATORS | ELI LILLY AND COMPANY (US) | 2002-09-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248919-A1 | Fluorinated trienes and their use as rxr modulators | RXRA, THRA, RXRB | KMT2A 3705/4885NPC1 400/4885MEN1 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.