SCHEMBL4366554

SCHEMBL4366554

[c]1cc(SSc2c[c]ncc2)ccn1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
DDAH1 O94760 1/20 0.32
NOS1 P29475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4837734 0.75
SCHEMBL4907036 0.69 LMNA (0.35)
SCHEMBL332270 0.65
SCHEMBL207328 0.65
SCHEMBL1515182 0.65
Water SCHEMBL16432603 0.63
Water SCHEMBL16432118 0.63
Hydrochloric Acid SCHEMBL28206004 0.63
SCHEMBL27277444 0.62
SCHEMBL4932430 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114437233-A Directional synthesis method of polypeptide dimer 湖北健翔生物制药有限公司 2022-05-06 CN claimed
US-7619121-B2 Method for isolating a thiol UNIVERSITY OF CAPE TOWN (ZA) 2009-11-17 US disclosed
US-20070232836-A1 Method for Isolating a Thiol UNIVERSITY OF CAPE TOWN (ZA) 2007-10-04 US disclosed
WO-2005021493-A2 A METHOD OF ISOLATING A THIOL UNIVERSITY OF CAPE TOWN (ZA) 2005-03-10 WO disclosed
EP-0793510-A4 METHODS FOR USE OF NOVEL LYOPROTECTANTS AND INSTANT KIT FORMULATIONS FOR RADIOPHARMACEUTICALS USING THE SAME CYTOGEN CORP (US) 2000-04-12 EP disclosed
US-5942210-A MIXING A DRUG, E.G. A RADIOPHARMACEUTICAL, PROTEIN, WITH N-(TRIS(HYDROXYMETHYL)METHYL)GLYCINE IN AN AQUEOUS SOLUTION IN WHICH THE GLYCINE DERIVATIVE DOES NOT ACT AS A BUFFER; ANTIAGGLOMERANTS; STABILIZATION CYTOGEN CORPORATION (US) 1999-08-24 US disclosed
EP-0793510-A1 METHODS FOR USE OF NOVEL LYOPROTECTANTS AND INSTANT KIT FORMULATIONS FOR RADIOPHARMACEUTICALS USING THE SAME CYTOGEN CORPORATION (US) 1997-09-10 EP disclosed
WO-1996014879-A9 METHODS FOR USE OF NOVEL LYOPROTECTANTS AND INSTANT KIT FORMULATIONS FOR RADIOPHARMACEUTICALS USING THE SAME 1996-09-06 WO disclosed
WO-1996014879-A1 METHODS FOR USE OF NOVEL LYOPROTECTANTS AND INSTANT KIT FORMULATIONS FOR RADIOPHARMACEUTICALS USING THE SAME CYTOGEN CORPORATION (US) 1996-05-23 WO disclosed