⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907036 | 0.71 | LMNA (0.35) | — | |
| SCHEMBL1244340 | 0.67 | — | — | |
| SCHEMBL207328 | 0.67 | — | — | |
| SCHEMBL1515182 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28206004 | 0.65 | — | — | |
| SCHEMBL4366554 | 0.65 | MEN1 (0.43) | — | |
| Water SCHEMBL16432603 | 0.65 | — | — | |
| SCHEMBL20239937 | 0.65 | DYRK1A (0.47) | — | |
| SCHEMBL28905656 | 0.64 | CA2 (0.39) | — | |
| SCHEMBL3311686 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | claimed |
| US-20200071326-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS INC (US) | 2020-03-05 | — | — | US | claimed |
| WO-2018191587-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | claimed |
| EP-3363788-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | claimed |
| US-9133157-B2 | HIV protease inhibitors | MERCK CANADA INC. (CA) | 2015-09-15 | — | — | US | claimed |
| US-9090593-B2 | Bicyclic compounds as Pim inhibitors | AMGEN INC. (US) | 2015-07-28 | — | — | US | claimed |
| EP-2796456-A1 | Bicyclic compounds as Pim inhibitors | Amgen Inc. (US) | 2014-10-29 | — | — | EP | claimed |
| US-20140303171-A1 | HIV PROTEASE INHIBITORS | MERCK CANADA INC. (CA) | 2014-10-09 | — | — | US | claimed |
| EP-2771332-A1 | HIV PROTEASE INHIBITORS | Merck Canada Inc. (CA) | 2014-09-03 | — | — | EP | claimed |
| EP-0324543-A2 | Antiarrhythmic agents | Pfizer Limited (GB) | 1989-07-19 | — | — | EP | claimed |
| US-4835165-A | Antiarrhythmic 4-phenylpiperidines | PFIZER INC. (US) | 1989-05-30 | — | — | US | claimed |
| US-4806536-A | Piperazinyl-substituted pyridine and imidazole anti-arrhythmic agents | PFIZER, INC. (US) | 1989-02-21 | — | — | US | claimed |
| US-4788196-A | Phenyl piperazine anti-arrhythmia agents | PFIZER INC. (US) | 1988-11-29 | — | — | US | claimed |
| EP-0291210-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1988-11-17 | — | — | EP | claimed |
| US-4769325-A | 2-(Allenyl)penicillins | BALDWIN JACK E (GB) | 1988-09-06 | — | — | US | claimed |
| EP-0244115-A2 | Phenyl-piperazine anti-arrhythmia agents | Pfizer Limited (GB) | 1987-11-04 | — | — | EP | claimed |
| EP-0233051-A2 | Antiarrhythmic Agents | Pfizer Limited (GB) | 1987-08-19 | — | — | EP | claimed |
| EP-0218323-A1 | 2-Propadienyl penicillin derivatives and intermediates | Baldwin, Jack Edward (GB) | 1987-04-15 | — | — | EP | claimed |
| US-4500525-A | CARDIOTONIC, HYPOTENSIVE, NEUROLEPTIC, ANALGESIC, ANTIINFLAMMATORYAGENTS, AND CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1985-02-19 | — | — | US | claimed |