SCHEMBL4366607

SCHEMBL4366607

Nc1ccc(-c2ccc(N)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1.[NaH]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.53
ALDH1A1 P00352 8/20 0.50
TDP1 Q9NUW8 5/20 0.50
RECQL P46063 3/20 0.50
POLB P06746 3/20 0.50
CASP6 P55212 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
NSD2 O96028 3/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
APEX1 P27695 1/20 0.50
APOBEC3A P31941 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ELAVL1 Q15717 1/20 0.47
TSHR P16473 4/20 0.46
NT5E P21589 3/20 0.46
HSD17B10 Q99714 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL602279 1.00 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL229927 0.98 RAPGEF4 (0.55) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL8489527 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Ammonia Solution, Strong SCHEMBL7552565 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Ammonia Solution, Strong SCHEMBL7552557 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Water SCHEMBL30927594 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL602281 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Lithium SCHEMBL8489531 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL4366615 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Trimethylammonium SCHEMBL7550408 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1RECQLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115685566-A Device for generating annular structured light and preparation method thereof 南京大学 2023-02-03 CN disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
EP-0254294-B1 METHOD OF PROCESSING A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL AND A COLOR DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1992-12-23 EP disclosed
US-5064751-A Stability, antifogging FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
EP-0254294-A2 Method of processing a silver halide color photographic material and a color developer FUJI PHOTO FILM CO., LTD. (JP) 1988-01-27 EP disclosed