SCHEMBL602279

SCHEMBL602279

Nc1ccc(-c2ccc(N)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1.[NaH].[NaH]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.53
ALDH1A1 P00352 8/20 0.50
TDP1 Q9NUW8 5/20 0.50
RECQL P46063 3/20 0.50
POLB P06746 3/20 0.50
CASP6 P55212 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
NSD2 O96028 3/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
APEX1 P27695 1/20 0.50
APOBEC3A P31941 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ELAVL1 Q15717 1/20 0.47
TSHR P16473 4/20 0.46
NT5E P21589 3/20 0.46
HSD17B10 Q99714 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4366607 1.00 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL229927 0.98 RAPGEF4 (0.55) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL8489527 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Ammonia Solution, Strong SCHEMBL7552565 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Ammonia Solution, Strong SCHEMBL7552557 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Water SCHEMBL30927594 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL602281 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Lithium SCHEMBL8489531 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
SCHEMBL4366615 0.96 RAPGEF4 (0.53) RAPGEF4ALDH1A1TDP1RECQLPOLB
Trimethylammonium SCHEMBL7550408 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1TDP1RECQLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785362-B2 Triazine derivative dye transfer inhibitors, washing products containing the same and uses therefor HENKEL AG & CO. KGAA (DE) 2014-07-22 US disclosed
US-8263541-B2 comprising a dye transfer inhibitor selected from triazine derivatives such as N,N'-bis-[2-chloro-4(sulfonaphth-1-yl-amino)-triazin-6-yl]-1,2-diaminoethane, optionally mixed with polymers and an aqueous solution of surfactants; colorfastness HENKEL AG & CO. KGAA (DE) 2012-09-11 US disclosed
US-20120196785-A1 TRIAZINE DERIVATIVE DYE TRANSFER INHIBITORS, WASHING PRODUCTS CONTAINING THE SAME AND USES THEREFOR HENKEL AG & CO. KGAA (DE) 2012-08-02 US disclosed
US-20120040881-A1 GRAYING-INHIBITING WASHING AGENT Henkel AG & KGaA (DE) 2012-02-16 US disclosed
US-20080234167-A1 Colour Protection Washing Product HENKEL KGAA (DE) 2008-09-25 US disclosed
US-4122088-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-10-24 US disclosed
US-4119784-A Anionic substituted sulfonamido biphenyls AMERICAN CYANAMID COMPANY (US) 1978-10-10 US disclosed
US-4107202-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040881-A1 GRAYING-INHIBITING WASHING AGENT WASHC5, GYPA, ACHE RAPGEF4 2907/4885ALDH1A1 3921/4885TDP1 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.