Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 10/20 | 0.54 |
| ▸ | NOS3 | P29474 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 5/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104037 | 1.00 | NOS2 (0.57) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL80890 | 1.00 | NOS2 (0.57) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL4362928 | 1.00 | NOS2 (0.57) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL1736042 | 0.81 | CYP2C19 (0.59) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL29613341 | 0.81 | CYP2C19 (0.59) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL1736416 | 0.81 | CYP2C19 (0.59) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL29794337 | 0.79 | CYP2C19 (0.56) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL1736266 | 0.78 | NPY1R (0.55) | NOS2CYP2C19CYP1A2TSHRGLA | |
| Tilarginine SCHEMBL23099403 | 0.78 | NOS1 (0.69) | NOS2CYP2C19CYP1A2TSHRGLA | |
| SCHEMBL1736695 | 0.78 | NOS2 (0.68) | NOS2CYP2C19CYP1A2TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |