SCHEMBL436685

SCHEMBL436685

Brc1ccoc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27936509 0.97
Formic Acid SCHEMBL27770735 0.84 CHRNB2 (0.31)
Toluene SCHEMBL28201229 0.81 LMNA (0.48)
SCHEMBL21564370 0.73 CHRM2 (0.45)
SCHEMBL15791703 0.69
SCHEMBL11063525 0.69
SCHEMBL15443283 0.69
SCHEMBL9769135 0.69
SCHEMBL3189480 0.69
SCHEMBL7079516 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP claimed
CN-108350034-B Antimicrobial polymyxin derived compounds 莫纳什大学 2022-03-11 CN claimed
CN-106117169-B A kind of synthetic method of 2,5- furandicarboxylic acids 绵阳高新区达高特科技有限公司 2018-08-17 CN claimed
CN-106883248-A A kind of small molecule material preparation method and applications based on condensed ring furans 中国科学院大学 2017-06-23 CN claimed
CN-106117169-A A kind of synthetic method of 2,5 furandicarboxylic acids 绵阳高新区达高特科技有限公司 2016-11-16 CN claimed
CN-101974023-B Rare earth complex, catalyst and preparation method thereof, and preparation method of polybutadiene CHANGCHUN APPLIED CHEMISTRY 2012-05-23 CN claimed
CN-101824114-B Sulfoacid rare earth catalyst for polymerizing high-cis-isoprene rubber and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2011-09-28 CN claimed
CN-101974023-A Rare earth complex, catalyst, preparation method thereof and preparation method of polybutadiene CHANGCHUN APPLIED CHEMISTRY 2011-02-16 CN claimed
CN-101824114-A Sulfoacid rare earth catalyst for polymerizing high-cis-isoprene rubber and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2010-09-08 CN claimed
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP disclosed
CN-117983305-A Catalyst containing aromatic heterocycle-aliphatic ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN disclosed
CN-111747964-B Organic electroluminescent compound, organic electroluminescent device and application thereof 南京高光半导体材料有限公司 2022-11-01 CN disclosed
EP-4053124-A1 FIVE-MEMBERED HETEROCYCLIC OXOCARBOXYLIC ACID COMPOUND AND MEDICAL USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2022-09-07 EP disclosed
WO-2022129047-A2 NOVEL MODULATORS OF THE NMDA RECEPTOR H. LUNDBECK A/S (DK) 2022-06-23 WO disclosed
CN-1161691-A Polymer containing conjugated N-fluoropyridinium salt and use thereof DAIKIN IND LTD (JP) 1997-10-08 CN disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed
EP-0679157-A1 NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS G.D. SEARLE & CO. (US) 1995-11-02 EP disclosed
WO-1994015932-A1 NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS G.D. SEARLE & CO. (US) 1994-07-21 WO disclosed
US-4454320-A Process for 5-substituted dialuric acids PFIZER INC. (US) 1984-06-12 US disclosed
US-3714197-A PROCESS FOR THE PREPARATION OF 2,3-DIBROMFURAN FOURNIER INNOVATION ET SYYNERGIE (FR) 1973-01-30 US disclosed