Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.93 |
| ▸ | EYA2 | O00167 | 1/20 | 0.93 |
| ▸ | APP | P05067 | 1/20 | 0.93 |
| ▸ | ACE | P12821 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 2/20 | 0.88 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.88 |
| ▸ | TSHR | P16473 | 2/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.88 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.88 |
| ▸ | DRD1 | P21728 | 1/20 | 0.88 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.88 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.88 |
| ▸ | DRD3 | P35462 | 1/20 | 0.88 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.88 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL285310 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL4367072 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL42055 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL4533309 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL3957470 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Pentetic Acid SCHEMBL9130818 | 0.97 | TDP1 (0.94) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL769944 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1535271 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL531146 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL121502 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930318-B1 | Process for producing diphenyl sulfone compound | NIPPON SODA CO (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-1273570-B1 | PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND | NIPPON SODA CO (JP) | 2013-07-17 | — | — | EP | disclosed |
| CN-1911909-B | Process for preparing diphenylsulfone compounds | NIPPON SODA CO | 2012-05-02 | — | — | CN | disclosed |
| CN-1911908-B | Process for preparing diphenylsulfone compounds | NIPPON SODA CO | 2012-05-02 | — | — | CN | disclosed |
| US-7619120-B2 | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO., LTD. (JP) | 2009-11-17 | — | — | US | disclosed |
| EP-1930318-A2 | Process for producing diphenyl sulfone compound | Nippon Soda Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
| CN-100383117-C | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2008-04-23 | — | — | CN | disclosed |
| CN-100341851-C | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2007-10-10 | — | — | CN | disclosed |
| CN-1318399-C | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2007-05-30 | — | — | CN | disclosed |
| CN-1911908-A | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2007-02-14 | — | — | CN | disclosed |
| CN-1911909-A | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2007-02-14 | — | — | CN | disclosed |
| CN-1273447-C | Process for preparing diphenylsulfone compounds | NIPPON SODA CO (JP) | 2006-09-06 | — | — | CN | disclosed |
| CN-1749245-A | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2006-03-22 | — | — | CN | disclosed |
| CN-1740148-A | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2006-03-01 | — | — | CN | disclosed |
| CN-1740149-A | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO (JP) | 2006-03-01 | — | — | CN | disclosed |
| US-20050065377-A1 | Processes for the preparation of diphenylsulfone compounds | NIPPON SODA CO., LTD | 2005-03-24 | — | — | US | disclosed |
| US-6831201-B2 | Aqueous solution containing dihydroxydiphenyl sulfone monoether compound is adjusted pH to a preset value, extracted with an organic solvent and separated to an organic and an aqueous layers, and that water or water adjusted to a fixed pH | NIPPON SODA CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| CN-1455768-A | Process for preparing diphenylsulfone compounds | NIPPON SODA CO (JP) | 2003-11-12 | — | — | CN | disclosed |
| US-20030092941-A1 | Process for producing diphenyl sulfone compound | NIPPON SODA CO., LTD. (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1273570-A1 | PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND | NIPPON SODA CO., LTD. (JP) | 2003-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092941-A1 | Process for producing diphenyl sulfone compound | ASH2L, AP2S1, HACL2 | TDP1 4771/4885EYA2 4607/4885APP 3660/4885 |
| US-20050065377-A1 | Processes for the preparation of diphenylsulfone compounds | AP2S1, ASH2L, SRMS | TDP1 4812/4885EYA2 4640/4885APP 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.