Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 10/20 | 0.39 |
| ▸ | NOS2 | P35228 | 10/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698170 | 0.87 | NOS1 (0.36) | NOS1NOS2NOS3SCN2A | |
| SCHEMBL11138004 | 0.86 | SCN2A (0.36) | NOS1NOS2NOS3SCN2ASPHK1 | |
| SCHEMBL4665788 | 0.86 | SCN2A (0.36) | NOS1NOS2NOS3SCN2ASPHK1 | |
| SCHEMBL20954138 | 0.86 | SCN2A (0.36) | NOS1NOS2NOS3SCN2ASPHK1 | |
| SCHEMBL20954129 | 0.86 | SCN2A (0.36) | NOS1NOS2NOS3SCN2ASPHK1 | |
| SCHEMBL8022095 | 0.83 | GBA1 (0.36) | SCN2ASPHK1 | |
| SCHEMBL8031333 | 0.83 | GBA1 (0.36) | SCN2ASPHK1 | |
| SCHEMBL8022112 | 0.83 | GBA1 (0.36) | SCN2ASPHK1 | |
| SCHEMBL8035667 | 0.83 | GBA1 (0.36) | SCN2ASPHK1 | |
| SCHEMBL8031468 | 0.83 | GBA1 (0.36) | SCN2ASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| EP-1879455-A1 | INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES | Bayer CropScience AG (DE) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119411-A1 | INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209422-A1 | Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives | DDT, AADAC, DDC | NOS1 3607/4885NOS2 3543/4885NOS3 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.