Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648915 | 0.86 | CYP1A2 (0.38) | GPR84FFAR1FFAR4PLA2G2C | |
| SCHEMBL29118740 | 0.85 | GPR84 (0.38) | GPR84FFAR1FFAR4 | |
| SCHEMBL9753360 | 0.83 | GPR84 (0.37) | GPR84FFAR1PLA2G2CMAPTLCK | |
| SCHEMBL29061782 | 0.83 | GPR84 (0.37) | GPR84FFAR1PLA2G2CMAPTLCK | |
| SCHEMBL29061780 | 0.83 | GPR84 (0.37) | GPR84FFAR1PLA2G2CMAPTLCK | |
| SCHEMBL690535 | 0.82 | HSPD1 (0.49) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL455822 | 0.81 | GPR84 (0.40) | GPR84FFAR1PLA2G2CMAPTLCK | |
| SCHEMBL8935620 | 0.81 | GPR84 (0.40) | GPR84FFAR1PLA2G2CMAPTLCK | |
| SCHEMBL17820568 | 0.77 | USP2 (0.36) | GPR84FFAR1PLA2G2CHSPD1BLM | |
| SCHEMBL18007394 | 0.77 | USP2 (0.36) | GPR84FFAR1PLA2G2CHSPD1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579025-B2 | Anti-diabetic extract isolated from rauvolfia vomitoria and citrus aurantium, and methods of using same | CAMPBELL-TOFTE JOAN | 2009-08-25 | — | — | US | disclosed |
| US-20090041873-A1 | ANTI-DIABETIC EXTRACT ISOLATED FROM RAUVOLFIA VOMITORIA AND CITRUS AURANTIUM, AND METHODS OF USING SAME | CAMPBELL-TOFTE JOAN | 2009-02-12 | — | — | US | disclosed |
| US-7429395-B2 | Anti-diabetic extract isolated from Rauvolfia vomitoria and Citrus aurantium, and method of using same | CAMPBELL-TOFTE JOAN | 2008-09-30 | — | — | US | disclosed |
| CN-101094683-A | Anti-diabetic extracts isolated from rauvolfia vomitoria and citrus aurantium and methods of use thereof | CAMPELL TOFTE JOAN (DK) | 2007-12-26 | — | — | CN | disclosed |
| EP-1804815-A2 | ANTI-DIABETIC EXTRACT ISOLATED FROM RAUVOLFIA VOMITORIA AND CITRUS AURANTIUM, AND METHODS OF USING SAME | Campell-Tofte, Joan (DK) | 2007-07-11 | — | — | EP | disclosed |
| US-20060115543-A1 | Anti-diabetic extract isolated from Rauvolfia vomitoria and citrus aurantium, and method of using same | CAMPBELL-TOFTE JOAN | 2006-06-01 | — | — | US | disclosed |
| WO-2006046156-A2 | ANTI-DIABETIC EXTRACT ISOLATED FROM RAUVOLFIA VOMITORIA AND CITRUS AURANTIUM, AND METHODS OF USING SAME | CAMPBELL-TOFTE JOAN (DK) | 2006-05-04 | — | — | WO | disclosed |