Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19216921 | 0.88 | HTR6 (0.52) | HTR6KDM4EUBE2NALKL3MBTL1 | |
| SCHEMBL14662807 | 0.81 | KDM4E (0.50) | HTR6KDM4EUBE2NALKL3MBTL1 | |
| SCHEMBL4367745 | 0.77 | HTR6 (0.48) | HTR6KDM4EUBE2NL3MBTL1CYP19A1 | |
| SCHEMBL28493425 | 0.77 | KDM4E (0.66) | HTR6KDM4EUBE2NL3MBTL1POLB | |
| SCHEMBL3678959 | 0.76 | CA1 (0.51) | HTR6KDM4EUBE2NALKL3MBTL1 | |
| SCHEMBL19216923 | 0.76 | LMNA (0.52) | HTR6KDM4EUBE2NL3MBTL1POLB | |
| SCHEMBL13257973 | 0.74 | HTR6 (0.52) | HTR6KDM4EUBE2NL3MBTL1POLB | |
| SCHEMBL13257974 | 0.74 | HTR6 (0.53) | HTR6KDM4EUBE2NL3MBTL1POLB | |
| SCHEMBL29111266 | 0.73 | HTR6 (0.53) | HTR6KDM4EUBE2NALKL3MBTL1 | |
| SCHEMBL3210637 | 0.72 | HTR6 (0.84) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006089-A2 | A2 ADENOSINE RECEPTOR AGONISTS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-01-08 | — | — | WO | disclosed |