SCHEMBL4367964

SCHEMBL4367964

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(Br)cc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.74
MAPT P10636 4/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
HPGD P15428 2/20 0.74
HTT P42858 2/20 0.74
PRMT1 Q99873 2/20 0.74
TDP1 Q9NUW8 2/20 0.74
CYP2C19 P33261 1/20 0.74
RECQL P46063 1/20 0.74
BLM P54132 1/20 0.74
SMAD3 P84022 1/20 0.74
ACE2 Q9BYF1 1/20 0.74
ALDH1A1 P00352 3/20 0.52
ALOX12 P18054 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
CYP2C9 P11712 1/20 0.52
BRCA1 P38398 1/20 0.52
LMNA P02545 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31018371 0.96 FTO (0.68) FTOMAPTMEN1KMT2AHPGD
SCHEMBL22191880 0.92 FTO (0.71) FTOMAPTMEN1KMT2AHPGD
SCHEMBL27833470 0.91 FTO (0.83) FTOMAPTMEN1KMT2AHPGD
SCHEMBL27632590 0.91 FTO (0.66) FTOMAPTMEN1KMT2AHPGD
SCHEMBL31018343 0.89 FTO (0.67) FTOMAPTMEN1KMT2AHPGD
SCHEMBL11246318 0.88 FTO (0.58) FTOMAPTMEN1KMT2AHPGD
SCHEMBL19549132 0.86 FTO (0.57) FTOMAPTMEN1KMT2AHPGD
SCHEMBL28430641 0.86 FTO (0.74) FTOMAPTMEN1KMT2AHPGD
SCHEMBL3481609 0.86 FTO (0.55) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL29371199 0.85 FTO (1.00) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1166784-C Method for labeling ribonucleic acid and labeled RNA fragment obtained thereby �Ȱ���ϣ�¹�˾ 2004-09-15 CN claimed
CN-1391616-A Method for labeling ribonucleic acid and labeled RNA fragment obtained thereby BIO MERIEUX (FR) 2003-01-15 CN claimed
US-12228481-B2 Expansion microscopy compatible anchorable HandE staining for histopathology EXPANSION TECHNOLOGIES (US) 2025-02-18 US disclosed
US-20220074827-A1 EXPANSION MICROSCOPY COMPATIBLE ANCHORABLE H&E STAINING FOR HISTOPATHOLOGY EXPANSION TECHNOLOGIES (US) 2022-03-10 US disclosed
WO-2020142490-A1 EXPANSION MICROSCOPY COMPATIBLE ANCHORABLE H&E STAINING FOR HISTOPATHOLOGY EXPANSION TECHNOLOGIES (US) 2020-07-09 WO disclosed
WO-2020142490-A1 EXPANSION MICROSCOPY COMPATIBLE ANCHORABLE H&E STAINING FOR HISTOPATHOLOGY EXPANSION TECHNOLOGIES (US) 2020-07-09 WO disclosed
EP-1087983-B1 METHOD FOR MARKING A RIBONUCLEIC ACID BIO MERIEUX (FR) 2009-03-18 EP disclosed
EP-1260597-B1 Process for labeling a nucleic acid, including purification BIO MERIEUX (FR) 2009-02-25 EP disclosed
CN-1330662-C Method for labeling ribonucleic acid and labeled RNA fragment obtained thereby BIO MERIEUX (FR) 2007-08-08 CN disclosed
US-6921640-B2 Process for labeling a ribonucleic acid BIO MERIEUX (FR) 2005-07-26 US disclosed
US-20020187500-A1 Process for labeling a ribonucleic acid BIO MERIEUX 2002-12-12 US disclosed
EP-1260596-A2 Process for labeling a ribonucleic acid, including optional signal amplification, and labeled RNA fragments which are obtained by this process BIO MERIEUX (FR) 2002-11-27 EP disclosed
EP-1260597-A2 Process for labeling a nucleic acid, including purification, and labeled RNA fragments obtained by this process BIO MERIEUX (FR) 2002-11-27 EP disclosed
US-6376179-B1 FRAGMENTING RNA TO PRODUCE PLURALITY OF RNA FRAGMENTS HAVING FREED TERMINAL PHOSPHATES FOR FURTHER REACTION, LABELING FRAGMENTS AT FREED TERMINAL PHOSPHATES LOCATED AT 3' END AND/OR 5' END OF FRAGMENT BIO MERIEUX (FR) 2002-04-23 US disclosed
CN-1310722-A Method for marking a ribonucleic acid and resulting marked RNA fragments BIO MERIEUX (FR) 2001-08-29 CN disclosed
EP-1087983-A1 METHOD FOR MARKING A RIBONUCLEIC ACID AND RESULTING MARKED RNA FRAGMENTS BIO MERIEUX (FR) 2001-04-04 EP disclosed
WO-1999065926-A1 METHOD FOR MARKING A RIBONUCLEIC ACID AND RESULTING MARKED RNA FRAGMENTS BIO MERIEUX (FR) 1999-12-23 WO disclosed