SCHEMBL28430641

SCHEMBL28430641

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(Cl)cc21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.74
MAPT P10636 4/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
HPGD P15428 2/20 0.74
HTT P42858 2/20 0.74
TDP1 Q9NUW8 2/20 0.74
CYP2C19 P33261 1/20 0.74
RECQL P46063 1/20 0.74
BLM P54132 1/20 0.74
SMAD3 P84022 1/20 0.74
PRMT1 Q99873 1/20 0.74
ACE2 Q9BYF1 1/20 0.74
ALDH1A1 P00352 3/20 0.52
ALOX12 P18054 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
CYP2C9 P11712 1/20 0.52
BRCA1 P38398 1/20 0.52
LMNA P02545 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27833470 0.91 FTO (0.83) FTOMAPTMEN1KMT2AHPGD
SCHEMBL21175517 0.88 FTO (0.58) FTOMAPTMEN1KMT2AHPGD
SCHEMBL1209492 0.87 FTO (0.68) FTOMAPTMEN1KMT2AHPGD
SCHEMBL4367964 0.86 FTO (0.74) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL28633518 0.86 FTO (0.94) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL30272223 0.85 FTO (1.00) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL16533 0.85 FTO (1.00) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL29371199 0.85 FTO (1.00) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL29388667 0.85 FTO (1.00) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL3645090 0.85 FTO (1.00) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117701675-A Stable formulations for luminescent detection of luciferases and nucleoside phosphates 普洛麦格公司 2024-03-15 CN disclosed
CN-111004835-B Stable formulations for luminescent detection of luciferases and nucleoside phosphates 普洛麦格公司 2023-12-29 CN disclosed
CN-111004835-A Stable formulations for luminescent detection of luciferase and nucleoside phosphates 普洛麦格公司 2020-04-14 CN disclosed
CN-105121653-B Stable formulations for luminescent detection of luciferase and nucleoside phosphates 普洛麦格公司 2020-01-24 CN disclosed