Pseudoephedrine

Pseudoephedrine

SCHEMBL4368

CN[C@@H](C)[C@@H](O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC6A2

The experimentally established mechanism targets of Pseudoephedrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 3/20 0.49
CYP2D6 P10635 3/20 1.00
ADRA2C P18825 2/20 1.00
CYP3A4 P08684 2/20 1.00
CYP2C19 P33261 2/20 1.00
CHRM2 P08172 1/20 1.00
ADRA1A P35348 1/20 1.00
RGS12 O14924 1/20 1.00
GLA P06280 1/20 1.00
CYP2C9 P11712 1/20 1.00
PKM P14618 1/20 1.00
ALOX15 P16050 1/20 1.00
TSHR P16473 1/20 1.00
ALOX12 P18054 1/20 1.00
NFKB1 P19838 1/20 1.00
HTR2A P28223 1/20 1.00
THPO P40225 1/20 1.00
GNAI1 P63096 1/20 1.00
HSD17B10 Q99714 1/20 1.00
KMT2A Q03164 2/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racephedrine SCHEMBL2633794 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Ephedrine SCHEMBL4785 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Ephedrine SCHEMBL30411556 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Racephedrine SCHEMBL8098202 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Racephedrine SCHEMBL11906521 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Racephedrine SCHEMBL4786 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Ephedrine SCHEMBL4731265 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Racephedrine SCHEMBL12573578 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Racephedrine SCHEMBL4369 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2
Racephedrine SCHEMBL420779 1.00 CYP2D6 (1.00) CYP2D6ADRA2CCYP3A4CYP2C19CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 29566 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3607938-B1 PHARMACEUTICAL COMPOSITION SOVIC BRKICIC LJILJANA (HR) 2026-05-27 EP claimed
CN-122094963-A Cardioprotective lipids and methods of use 2026-05-26 CN claimed
WO-2026104388-A1 DECONGESTANT CONTROLLED RELEASE DRUG DELIVERY SYSTEM FAES FARMA, S.A. (ES) 2026-05-21 WO claimed
US-12631647-B2 Lock and key templation of molecularly imprinted polymer for small molecule recognition Genesee Valley Innovations, LLC (US) 2026-05-19 US claimed
US-12629422-B2 Agave syrup formulation or suspension for active pharmaceutical agents GENEXA INC. (US) 2026-05-19 US claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
EP-4734952-A1 ORAL TABLET WITH IMPROVED UNIFORMITY OF CONTENT OF ACTIVES Fertin Pharma A/S (DK) 2026-05-06 EP claimed
US-12617809-B2 Cardioprotective lipid and method of use SIGNPATH PHARMA, INC. (US) 2026-05-05 US claimed
EP-4731194-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP Technologies, Inc. (US) 2026-04-29 EP claimed
US-20260108531-A1 Methods of Treating Hypogonadism with Transnasal Testosterone Bio-adhesive Gel Formulations in Males with Allergic Rhinitis and Methods for Preventing an Allergic Rhinitis Event ACERUS BIOPHARMA INC (CA) 2026-04-23 US claimed
US-4552899-A ANTITUSSIVE AGENTS ANALGESIC ASSOCIATES (US) 1985-11-12 US claimed
WO-1985004589-A1 COUGH/COLD MIXTURES COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS SUNSHINE ABRAHAM 1985-10-24 WO claimed
EP-0153836-A2 Dry, water-foamable pharmaceutical compositions HEALTH PRODUCTS DEVELOPMENT INC. (US) 1985-09-04 EP claimed
EP-0132472-A1 Medicated products containing a magnesium trisilicate adsorbent with a medicament drug adsorbed thereon WARNER-LAMBERT COMPANY (US) 1985-02-13 EP claimed
US-4369172-A Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose FOREST LABORATORIES INC. (US) 1983-01-18 US claimed
US-4277420-A Ephedrine and pseudoephedrine precursors MONSANTO COMPANY (US) 1981-07-07 US claimed
US-4260596-A Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same BRISTOL-MYERS COMPANY (US) 1981-04-07 US claimed
US-4221778-A ION EXCHANGE RESINS, ANTISWELLING AGENTS PENNWALT CORPORATION (US) 1980-09-09 US claimed
US-4205060-A Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use PENNWALT CORPORATION (US) 1980-05-27 US claimed
US-RE29875-E THEOPHYLLINE SOLUBILIZED BY GLYCERYL GUAIACOLATE, POTASSIUM GUAIACOL SULFONATE OR GUAIACOL MEAD JOHNSON & COMPANY (US) 1979-01-02 US claimed