Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436893 | 0.88 | ALDH1A1 (0.77) | ALDH1A1MAPTNPSR1HPGDSMN1; SMN2 | |
| SCHEMBL31424563 | 0.87 | ALDH1A1 (0.81) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL469041 | 0.83 | GAA (0.48) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL11774581 | 0.83 | USP2 (0.62) | ALDH1A1NPSR1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL17089348 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTGAAHPGDKDM4E | |
| SCHEMBL9308052 | 0.80 | GAA (0.76) | ALDH1A1MAPTGAAHPGDKDM4E | |
| SCHEMBL8048430 | 0.80 | ALDH1A1 (0.96) | ALDH1A1MAPTGAAHPGDKDM4E | |
| SCHEMBL9066249 | 0.80 | ALDH1A1 (0.96) | ALDH1A1MAPTGAAHPGDKDM4E | |
| SCHEMBL9307243 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL5508657 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139456-B2 | Chelating compounds and immobilized tethered chelators | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-09-22 | — | — | US | disclosed |
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2012-03-15 | — | — | US | disclosed |
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2012-03-15 | — | — | US | disclosed |
| US-8066883-B2 | Removing aluminum from solution using chelating compounds and immobilized tethered chelators | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-8066883-B2 | Removing aluminum from solution using chelating compounds and immobilized tethered chelators | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110168636-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-07-14 | — | — | US | disclosed |
| US-20110168636-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-07-14 | — | — | US | disclosed |
| US-7932326-B2 | Chelating compounds and immobilized tethered chelators | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, TTPA, SLC39A7 | ALDH1A1 3904/4885MAPT 2716/4885NPSR1 1363/4885 |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, SLC30A7, SLC39A7 | ALDH1A1 3115/4885MAPT 3260/4885NPSR1 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.