Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576542 | 0.83 | HSD17B10 (0.39) | NOX1KMT2AATMHSD17B10 | |
| SCHEMBL7503466 | 0.77 | — | — | |
| SCHEMBL4374691 | 0.73 | MEN1 (0.32) | KMT2AHSD17B10 | |
| SCHEMBL20274462 | 0.70 | TDP1 (0.35) | HSD17B10TDP1 | |
| SCHEMBL14435586 | 0.69 | TDP1 (0.33) | TDP1 | |
| SCHEMBL4854363 | 0.69 | NOX1 (0.30) | NOX1KMT2A | |
| SCHEMBL8734993 | 0.68 | MEN1 (0.36) | NOX1KMT2A | |
| SCHEMBL18661726 | 0.68 | HSD17B10 (0.34) | HSD17B10 | |
| SCHEMBL11129794 | 0.67 | TDP1 (0.36) | KMT2AHSD17B10ESR1TDP1 | |
| SCHEMBL17302204 | 0.67 | KDM4E (0.32) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |