Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735431 | 0.80 | MEN1 (0.34) | MEN1MAPTHTTKMT2A | |
| SCHEMBL188694 | 0.72 | MEN1 (0.41) | MEN1MAPTHTTKMT2A | |
| SCHEMBL69958 | 0.71 | ESR1 (0.32) | — | |
| SCHEMBL22374154 | 0.71 | — | — | |
| SCHEMBL28140273 | 0.68 | ESR1 (0.31) | — | |
| SCHEMBL8085043 | 0.68 | ESR1 (0.31) | — | |
| SCHEMBL4861622 | 0.67 | MEN1 (0.30) | MEN1MAPTHTTKMT2A | |
| SCHEMBL31290292 | 0.67 | — | — | |
| SCHEMBL134038 | 0.67 | HPGD (0.44) | MEN1MAPTKMT2A | |
| SCHEMBL4311227 | 0.66 | MEN1 (0.33) | MEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2015181544-A2 | CHEMICALLY MODIFYING PEPTIDES | THE UNIVERSITY OF DURHAM (GB) | 2015-12-03 | — | — | WO | disclosed |
| EP-0824096-A2 | Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters | Akzo Nobel N.V. (NL) | 1998-02-18 | — | — | EP | disclosed |