Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367741 | 0.78 | CA1 (0.56) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL2832043 | 0.77 | CA1 (0.63) | CA1CA2CA9ALDH1A1MAPT | |
| Hydrogen Sulfide SCHEMBL16581552 | 0.75 | CA1 (0.61) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL22518679 | 0.74 | CA1 (0.66) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL5269347 | 0.74 | CA2 (0.70) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL2990592 | 0.72 | CA1 (0.68) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL22518680 | 0.72 | CA1 (0.61) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL28375986 | 0.71 | CA2 (1.00) | CA1CA2CA9KIF11 | |
| SCHEMBL575851 | 0.71 | CA2 (0.41) | CA1CA2CA9KIF11RAB9A | |
| SCHEMBL5269351 | 0.71 | CA1 (0.66) | CA1CA2CA9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073427-A1 | FLUORINATED ALKANESULFONIC ACID ESTERS AND AMIDES AND PROCESSES FOR MAKING AND USING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009073426-A2 | FLUORINATED ALKANESULFONIC ACID ANHYDRIDES AND PROCESSES FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20090137831-A1 | Fluorinated Alkanesulfonic Acid Esters and Amides and Processes for Making and Using the Same | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-28 | — | — | US | disclosed |
| US-20090137840-A1 | Fluorinated Alkanesulfonic Acid Anhydrides and Processes for Making the Same | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-28 | — | — | US | disclosed |
| EP-1827420-A4 | OCTAHYDROPYRANO[3,4-C]PYRROLE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1827420-A2 | OCTAHYDROPYRANO[3,4-C]PYRROLE TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006065711-A2 | OCTAHYDROPYRANO[3,4-C]PYRROLE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2006-06-22 | — | — | WO | disclosed |