SCHEMBL2832043

SCHEMBL2832043

CC(C)(C)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.63
CA2 P00918 3/20 0.63
CA9 Q16790 3/20 0.63
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 4/20 0.45
MAPT P10636 4/20 0.45
CXCR2 P25025 2/20 0.45
MEN1 O00255 1/20 0.45
RECQL P46063 1/20 0.45
KMT2A Q03164 1/20 0.45
KIF11 P52732 1/20 0.44
CXCR1 P25024 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSD11B1 P28845 1/20 0.42
HSD17B3 P37058 1/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL16581552 0.98 CA1 (0.61) CA1CA2CA9SMN1; SMN2ALDH1A1
Biphenyl SCHEMBL112616 0.91 CA1 (0.54) CA1CA2CA9SMN1; SMN2ALDH1A1
Biphenyl SCHEMBL4512369 0.90 CA1 (0.53) CA1CA2CA9SMN1; SMN2ALDH1A1
Biphenyl SCHEMBL710425 0.90 CA1 (0.53) CA1CA2CA9SMN1; SMN2ALDH1A1
SCHEMBL3842500 0.88 PTPN11 (0.50) CA1CA2CA9SMN1; SMN2CXCR2
Diphenylsulfane SCHEMBL2191112 0.87 CA1 (0.50) CA1CA2CA9SMN1; SMN2ALDH1A1
SCHEMBL576035 0.85 CA2 (0.50) CA1CA2CA9CXCR2KIF11
SCHEMBL1473787 0.85 CA2 (0.46) CA1CA2CA9ALDH1A1MAPT
Tromethamine SCHEMBL5359436 0.84 CA1 (0.51) CA1CA2CA9SMN1; SMN2ALDH1A1
SCHEMBL15946067 0.84 CA1 (0.46) CA1CA2CA9SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790985-B1 METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS VIBRANT HOLDINGS LLC (US) 2026-04-15 EP claimed
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN claimed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN claimed
EP-3004120-B1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION UNIV NANYANG TECH (SG) 2018-08-29 EP claimed
CN-105658656-A 1, 1' -spiroindane-7, 7-bisphosphine oxides as highly active supporting ligands in palladium-catalyzed asymmetric Heck reactions 南洋理工大学 2016-06-08 CN claimed
US-20160136629-A1 SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-05-19 US claimed
CN-100595673-C Positive type photosensitive paste composition for PDP electrode, PDP electrode prepared therefrom, and PDP comprising the PDP electrode SAMSUNG SDI CO LTD 2010-03-24 CN claimed
CN-1779570-A Positive type photosensitive paste composition for PDP electrode, PDP electrode prepared therefrom, and PDP comprising the PDP electrode SAMSUNG SDI CO LTD (KR) 2006-05-31 CN claimed
CN-1241065-C Photoresist composite with optical acid-generating agent containing optical free radical generating agent HAIRYOKSA SEMICONDUCTOR CO LTD (KR) 2006-02-08 CN claimed
CN-1221856-C Polymer and forming method of micro pattern using the same HYUNDAI ELECTRONICS IND (KR) 2005-10-05 CN claimed
CN-1146602-C Polymer and forming method of micro pattern using the same 现代电子产业株式会社 2004-04-21 CN claimed
CN-1330288-A Photoresist composite with optical acid-generating agent containing optical free radical generating agent HAIRYOKSA SEMICONDUCTOR CO LTD (KR) 2002-01-09 CN claimed
CN-1238344-A Polymer and forming method of micro pattern using the same HYUNDAI ELECTRONICS IND (KR) 1999-12-15 CN claimed
CN-1235171-A Polymer and forming method of micro pattern using the same HYUNDAI ELECTRONICS IND (KR) 1999-11-17 CN claimed
CN-116594268-A Method for improving adhesiveness and/or developing speed of photoresist 华中科技大学 2023-08-15 CN disclosed
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN disclosed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN disclosed
US-5480883-A Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-01-02 US disclosed
US-5409930-A Inhibits abnoramal cell proliferation; dimethoxyquinoline/ dimethylquinoline/ quinolineoxide/ and quinoxaline derivatives RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1995-04-25 US disclosed
WO-1992020642-A1 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160136629-A1 SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION SBK1, SIK1, PDPK1 CA1 3165/4885CA2 2812/4885CA9 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.