SCHEMBL4369804

SCHEMBL4369804

CCCC(=O)[Si](CC)(C(=O)CCC)C(=O)CCC

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.48
HDAC1 Q13547 4/20 0.48
HDAC2 Q92769 4/20 0.48
HDAC8 Q9BY41 4/20 0.48
FFAR3 O14843 3/20 0.48
CES2 O00748 6/20 0.45
CES1 P23141 6/20 0.45
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.39
HDAC6 Q9UBN7 1/20 0.38
CTSD P07339 1/20 0.36
CA1 P00915 1/20 0.36
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14760245 0.77 CES2 (0.45) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL8023823 0.75 CES2 (0.50) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL4363414 0.73 CES2 (0.47) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL14503602 0.73
Butyric Acid SCHEMBL600203 0.69 FFAR3 (0.93) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL14759833 0.67 ALDH1A1 (0.42) HDAC3HDAC1HDAC2HDAC8FFAR3
Butyric Acid SCHEMBL6746198 0.67 FFAR3 (0.88) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL149763 0.65 ALDH1A1 (0.41) HDAC3HDAC1HDAC2HDAC8FFAR3
Butyric Acid SCHEMBL28462340 0.65
SCHEMBL25174 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1944277-B1 ANTIFOGGING ARTICLE ASAHI GLASS CO LTD (JP) 2017-04-05 EP disclosed
US-8227085-B2 Anti-fogging article and anti-fogging agent composition ASAHI GLASS COMPANY, LIMITED (JP) 2012-07-24 US disclosed
US-20120171476-A1 ANTI-FOGGING ARTICLE AND ANTI-FOGGING AGENT COMPOSITION ASAHI GLASS COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20090011244-A1 ANTI-FOGGING ARTICLE AND ANTI-FOGGING AGENT COMPOSITION ASAHI GLASS COMPANY, LIMITED (JP) 2009-01-08 US disclosed
EP-1944277-A1 ANTIFOGGING ARTICLE AND ANTIFOGGING AGENT COMPOSITION Asahi Glass Company, Limited (JP) 2008-07-16 EP disclosed