SCHEMBL999400

SCHEMBL999400

NCCOC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20513035 0.95
SCHEMBL436989 0.95
SCHEMBL3393452 0.81
SCHEMBL2780260 0.78 MEN1 (0.32)
SCHEMBL634253 0.73
SCHEMBL9952284 0.72
SCHEMBL17460346 0.72
SCHEMBL1397639 0.72
SCHEMBL15229626 0.71
SCHEMBL2818899 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117729941-A Dual amylin and calcitonin receptor agonists and uses thereof 伊莱利利公司 2024-03-19 CN claimed
CN-112608377-B GIP and GLP-1 co-agonist compounds 伊莱利利公司 2024-02-13 CN claimed
CN-117402219-A GLP-1/GIP double agonist and preparation method and application thereof 杭州中美华东制药有限公司 2024-01-16 CN claimed
CN-117320740-A GIP/GLP1 dual agonist treatment methods 伊莱利利公司 2023-12-29 CN claimed
US-20230372508-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. 2023-11-23 US claimed
WO-2023225650-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. (US) 2023-11-23 WO claimed
US-20230203558-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM ORIGINAL G B.V. (NL) 2023-06-29 US claimed
EP-4127206-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM Original G B.V. (NL) 2023-02-08 EP claimed
CN-115362262-A Diagnostic peptides for use in methods, kits and systems for diagnosing viral infections 奥里基诺G有限公司 2022-11-18 CN claimed
CN-115298207-A GIP/GLP1 co-agonist compounds 伊莱利利公司 2022-11-04 CN claimed
CN-109475592-B Novel fatty acid modified urocortin-2 analogs for the treatment of diabetes and chronic kidney disease 伊莱利利公司 2022-08-09 CN claimed
WO-2021198228-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM ORIGINAL G B.V. (NL) 2021-10-07 WO claimed
US-9808532-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-11-07 US claimed
US-20120134922-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US claimed
US-20120134931-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US claimed
EP-2453926-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP claimed
EP-2454271-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP claimed
WO-2011008992-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO claimed
WO-2011008996-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO claimed
US-20240168014-A1 METHOD FOR THE IN VITRO DIAGNOSIS OF INFECTION ORIGINAL G B.V. (NL) 2024-05-23 US disclosed
CN-111094331-B Acylated oxyntomodulin peptide analogues 东亚ST株式会社 2024-03-29 CN disclosed
CN-117729941-A Dual amylin and calcitonin receptor agonists and uses thereof 伊莱利利公司 2024-03-19 CN disclosed
CN-117642153-A Erodible tablet 伊莱利利公司 2024-03-01 CN disclosed
CN-117597135-A Application of Mazdutide 信达生物制药(苏州)有限公司 2024-02-23 CN disclosed
CN-112608377-B GIP and GLP-1 co-agonist compounds 伊莱利利公司 2024-02-13 CN disclosed
EP-4308929-A1 METHOD FOR THE IN VITRO DIAGNOSIS OF INFECTION Original G B.V. (NL) 2024-01-24 EP disclosed
CN-117402219-A GLP-1/GIP double agonist and preparation method and application thereof 杭州中美华东制药有限公司 2024-01-16 CN disclosed
CN-117320740-A GIP/GLP1 dual agonist treatment methods 伊莱利利公司 2023-12-29 CN disclosed
US-20230372508-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. 2023-11-23 US disclosed
WO-2023225650-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. (US) 2023-11-23 WO disclosed
CN-116940841-A Methods for in vitro diagnosis of infection 原始格私人有限公司 2023-10-24 CN disclosed
CN-116917312-A Long acting amylin receptor agonists and uses thereof 伊莱利利公司 2023-10-20 CN disclosed
CN-116854804-A Acylated oxyntomodulin peptide analogues 东亚ST株式会社 2023-10-10 CN disclosed
CN-110741242-B Ratio fluorescence imaging method 艾维拉斯生物科学公司 2023-07-07 CN disclosed
US-20230203558-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM ORIGINAL G B.V. (NL) 2023-06-29 US disclosed
EP-4127206-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM Original G B.V. (NL) 2023-02-08 EP disclosed
CN-115362262-A Diagnostic peptides for use in methods, kits and systems for diagnosing viral infections 奥里基诺G有限公司 2022-11-18 CN disclosed
CN-115298207-A GIP/GLP1 co-agonist compounds 伊莱利利公司 2022-11-04 CN disclosed
US-20220288223-A1 ACTIVATABLE SPECIFIC BINDING MEMBER COMPLEXES, AND METHODS OF MAKING AND USING SAME CALIFORNIA, THE REGENTS OF THE UNIVERSITY OF 2022-09-15 US disclosed
CN-114981295-A Polypeptide compound and application thereof 联邦生物科技(珠海横琴)有限公司 2022-08-30 CN disclosed
CN-109475592-B Novel fatty acid modified urocortin-2 analogs for the treatment of diabetes and chronic kidney disease 伊莱利利公司 2022-08-09 CN disclosed
CN-114787183-A Incretin analogue and application thereof 伊莱利利公司 2022-07-22 CN disclosed
US-11246940-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-15 US disclosed
WO-2021198228-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM ORIGINAL G B.V. (NL) 2021-10-07 WO disclosed
EP-3876196-A1 RATIOMETRIC FLUORESCENCE IMAGING METHODS Avelas Biosciences, Inc. (US) 2021-09-08 EP disclosed
US-11052160-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2021-07-06 US disclosed
CN-112469731-A GIP/GLP1 co-agonist compounds 伊莱利利公司 2021-03-09 CN disclosed
US-20200376013-A1 SELECTIVE DRUG DELIVERY COMPOSITIONS AND METHODS OF USE AVELAS BIOSCIENCES, INC. 2020-12-03 US disclosed
WO-2020186090-A2 ACTIVATABLE SPECIFIC BINDING MEMBER COMPLEXES, AND METHODS OF MAKING AND USING SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-09-17 WO disclosed
US-20200150041-A1 RATIOMETRIC FLUORESCENCE IMAGING METHODS AVELAS ACQUISITION CORPORATION 2020-05-14 US disclosed
US-10596259-B2 Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-03-24 US disclosed
CN-105102484-B Selective delivery molecules and methods of use 艾维拉斯生物科学公司 2020-03-10 CN disclosed
US-10570178-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2020-02-25 US disclosed
EP-3610243-A1 RATIOMETRIC FLUORESCENCE IMAGING METHODS Avelas Biosciences, Inc. (US) 2020-02-19 EP disclosed
US-20200046843-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-02-13 US disclosed
CN-110741242-A Ratiometric fluorescence imaging method 艾维拉斯生物科学公司 2020-01-31 CN disclosed
US-20190321496-A1 AGENTS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH EXTRACELLULAR MATRIX TURNOVER BAKER IDI HEART AND DIABETES INSTITUTE HOLDINGS LIMITED (AU) 2019-10-24 US disclosed
US-10385380-B2 Personalized protease assay to measure protease activity in neoplasms THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-08-20 US disclosed
CN-109922817-A The agent and method of relevant disease are had enough to meet the need to extracellular matrix for diagnosing and treating 贝克IDI心脏和糖尿病研究院控股有限公司 2019-06-21 CN disclosed
US-20190175021-A1 IMAGING SYSTEM AND METHOD FOR FLUORESCENCE GUIDED SURGERY UNIV CALIFORNIA (US) 2019-06-13 US disclosed
US-20190151481-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2019-05-23 US disclosed
US-20190119327-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2019-04-25 US disclosed
EP-3471748-A1 AGENTS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH EXTRACELLULAR MATRIX TURNOVER Baker IDI Heart and Diabetes Institute Holdings Ltd (AU) 2019-04-24 EP disclosed
EP-3473273-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE Avelas Biosciences, Inc. (US) 2019-04-24 EP disclosed
US-10239919-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2019-03-26 US disclosed
US-10231626-B2 Imaging system and method for fluorescence guided surgery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-03-19 US disclosed
US-10226539-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2019-03-12 US disclosed
US-10202422-B2 2019-02-12 US disclosed
WO-2018187629-A1 RATIOMETRIC FLUORESCENCE IMAGING METHODS AVELAS BIOSCIENCES, INC. (US) 2018-10-11 WO disclosed
US-10029017-B2 Pretargeted activatable cell penetrating peptide with intracellularly releasable prodrug THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-07-24 US disclosed
EP-2736533-B1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS BIOSCIENCES INC (US) 2018-07-04 EP disclosed
US-20180140703-A1 TUMOR RADIOSENSITIZATION WITH ANTIBODY CONJUGATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-05-24 US disclosed
US-20180057536-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2018-03-01 US disclosed
US-20180000971-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2018-01-04 US disclosed
WO-2017214681-A1 AGENTS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH EXTRACELLULAR MATRIX TURNOVER BAKER IDI HEART AND DIABETES INSTITUTE HOLDINGS LIMITED (AU) 2017-12-21 WO disclosed
US-9840537-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2017-12-12 US disclosed
US-9808532-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-11-07 US disclosed
US-20170305968-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-10-26 US disclosed
US-9782498-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2017-10-10 US disclosed
US-9682151-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-06-20 US disclosed
US-20170080088-A1 TUMOR RADIOSENSITIZATION WITH MONOMETHYL AURISTATIN E (MMAE) AND DERIVATIVES THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-03-23 US disclosed
US-20170044214-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2017-02-16 US disclosed
US-9504763-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2016-11-29 US disclosed
CN-103874512-B Selectively deliver molecule and using method 艾维拉斯生物科学公司 2016-11-16 CN disclosed
US-20160220707-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2016-08-04 US disclosed
US-9371367-B1 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2016-06-21 US disclosed
US-20160160263-A1 PERSONALIZED PROTEASE ASSAY TO MEASURE PROTEASE ACTIVITY IN NEOPLASMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-06-09 US disclosed
US-20160152670-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2016-06-02 US disclosed
US-20160082119-A1 SELECTIVE DRUG DELIVERY COMPOSITIONS AND METHODS OF USE AVELAS BIOSCIENCES, INC. 2016-03-24 US disclosed
US-9278144-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2016-03-08 US disclosed
EP-2988786-A1 SELECTIVE DRUG DELIVERY COMPOSITIONS AND METHODS OF USE Avelas Biosciences, Inc. (US) 2016-03-02 EP disclosed
US-20150359902-A1 PRETARGETED ACTIVATABLE CELL PENETRATING PEPTIDE WITH INTRACELLULARLY RELEASABLE PRODRUG NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-12-17 US disclosed
US-20150359908-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2015-12-17 US disclosed
EP-2951210-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE Avelas Biosciences, Inc. (US) 2015-12-09 EP disclosed
WO-2014120837-A9 PRETARGETED ACTIVATABLE CELL PENETRATING PEPTIDE WITH INTRACELLULARY RELEASEABLE PRODRUG THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-03-26 WO disclosed
US-20150031852-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS BIOSCIENCES, INC. (US) 2015-01-29 US disclosed
WO-2014176284-A1 SELECTIVE DRUG DELIVERY COMPOSITIONS AND METHODS OF USE AVELAS BIOSCIENCES, INC. (US) 2014-10-30 WO disclosed
US-20140276008-A1 IMAGING SYSTEM AND METHOD FOR FLUORESCENCE GUIDED SURGERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-09-18 US disclosed
WO-2014120837-A2 PRETARGETED ACTIVATABLE CELL PENETRATING PEPTIDE WITH INTRACELLULARY RELEASEABLE PRODRUG THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-08-07 WO disclosed
WO-2014120974-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS BIOSCIENCES, INC. (US) 2014-08-07 WO disclosed
EP-2736533-A2 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE Avelas Biosciences, Inc. (US) 2014-06-04 EP disclosed
WO-2013019681-A2 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS BIOSCIENCES, INC. (US) 2013-02-07 WO disclosed
US-20120134922-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US disclosed
US-20120134931-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US disclosed
EP-2453926-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP disclosed
EP-2454271-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP disclosed
WO-2011008992-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO disclosed
WO-2011008992-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO disclosed
WO-2011008996-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO disclosed