Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244247 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL5632532 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL7370116 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL4237733 | 0.80 | POLB (0.67) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7373131 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6962833 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6952636 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6958076 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL3513442 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL28127747 | 0.71 | ALOX5 (0.50) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061847-A2 | METHODS FOR DIAGNOSING AND TREATING PELVIC PAIN DISORDERS VIA BETA-CATENIN | UNIVERSITY OF ROCHESTER (US) | 2009-05-14 | — | — | WO | claimed |