Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370116 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL4369997 | 0.87 | SMN1; SMN2 (0.72) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL5632532 | 0.87 | SMN1; SMN2 (0.72) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL4237733 | 0.83 | POLB (0.67) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6962833 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7373131 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6952636 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL6958076 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL3513442 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL3510451 | 0.74 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | SMN1; SMN2 4143/4885L3MBTL1 2061/4885POLB 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.