Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404184 | 1.00 | PDK2 (0.47) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL29397249 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL29399278 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL29511719 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL783463 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL783450 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL996751 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL29574412 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL29530902 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 | |
| SCHEMBL29602609 | 0.89 | PDK2 (0.58) | PDK2S100A4CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4406944-B1 | SPIRO-TYPE HOLE TRANSPORT MATERIALS WITH EXTENDED EDGE PI-CONJUGATION LENGTH | TOYOTA MOTOR CO LTD (JP) | 2025-10-29 | — | — | EP | claimed |
| EP-4406944-A1 | SPIRO-TYPE HOLE TRANSPORT MATERIALS WITH EXTENDED EDGE PI-CONJUGATION LENGTH | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2024-07-31 | — | — | EP | claimed |
| CN-115505103-A | Conjugated microporous polymer, and organic amine catalytic synthesis method and application thereof | 华中科技大学 | 2022-12-23 | — | — | CN | claimed |
| CN-115286520-A | Preparation method of hole transport material Spiro-OMeTAD | 黑龙江省科学院石油化学研究院 | 2022-11-04 | — | — | CN | claimed |
| CN-110204696-B | Sulfur-containing porous organic polymer material LNUs and preparation method and application thereof | 辽宁大学 | 2022-03-29 | — | — | CN | claimed |
| CN-110256645-B | Spherical covalent organic framework material and preparation method and application thereof | 南京邮电大学 | 2021-10-26 | — | — | CN | claimed |
| CN-107917904-B | Rapid detection Fe3+Method (2) | 山东大学 | 2021-06-22 | — | — | CN | claimed |
| CN-107987093-B | Small molecule taking spirobifluorene as core and preparation method thereof | 武汉工程大学 | 2020-11-27 | — | — | CN | claimed |
| CN-110872261-A | Organic semiconductor material substituted by oxadiazole containing spirofluorene, preparation method and OLED device | 上海和辉光电有限公司 | 2020-03-10 | — | — | CN | claimed |
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | claimed |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2016-09-01 | — | — | US | claimed |
| EP-3052470-A1 | HOLE TRANSPORT MATERIAL | Merck Patent GmbH (DE) | 2016-08-10 | — | — | EP | claimed |
| WO-2015049031-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2015-04-09 | — | — | WO | claimed |
| EP-4406944-B1 | SPIRO-TYPE HOLE TRANSPORT MATERIALS WITH EXTENDED EDGE PI-CONJUGATION LENGTH | TOYOTA MOTOR CO LTD (JP) | 2025-10-29 | — | — | EP | disclosed |
| EP-4631926-A1 | METHOD FOR PRODUCING HOMO-COUPLING REACTION PRODUCT | National University Corporation Hokkaido University (JP) | 2025-10-15 | — | — | EP | disclosed |
| EP-3169722-B9 | NANOPARTICLES | CHROMITION LTD (GB) | 2025-06-18 | — | — | EP | disclosed |
| US-5840217-A | LIGHT-EMITTING, CHARGE-TRANSPORT, CHARGE-INJECTION MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| WO-1998018996-A1 | OPTICAL BRIGHTENING AGENT | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-05-07 | — | — | WO | disclosed |
| EP-0676461-A2 | Spiro compounds and their application as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
| US-5026894-A | Compound for use in the synthesis of semiconducting polymers with perpendicularly arranged cores and method of synthesizing said compound | UNIVERSITY OF SOUTH CAROLINA (US) | 1991-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | SUN2, SLC6A19, SLCO2A1 | PDK2 2494/4885S100A4 693/4885CA1 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.