Methacrylic Acid

Methacrylic Acid

SCHEMBL4370104

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)OCC(O)COc1ccc(C(C)(C)c2ccc(OCC(O)COC(=O)C(=C)C)cc2)cc1.CCOC(N)=O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
HTT P42858 4/20 0.43
HIF1A Q16665 1/20 0.43
AR P10275 2/20 0.42
KMT2A Q03164 5/20 0.42
KDM4E B2RXH2 4/20 0.42
MEN1 O00255 4/20 0.42
ALDH1A1 P00352 3/20 0.42
POLB P06746 3/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
USP2 O75604 1/20 0.39
RECQL P46063 1/20 0.39
MITF O75030 1/20 0.38
MAPK1 P28482 1/20 0.38
GAA P10253 1/20 0.37
APEX1 P27695 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL4370099 0.94 AR (0.47) CYP1A2HTTHIF1AARKMT2A
Methacrylic Acid SCHEMBL14881206 0.91 HTT (0.50) CYP1A2HTTHIF1AARKMT2A
SCHEMBL12265865 0.88 HTT (0.49) CYP1A2HTTHIF1AARKMT2A
Bicarbonate SCHEMBL7732697 0.88 HTT (0.51) CYP1A2HTTHIF1AARKMT2A
SCHEMBL14173202 0.88 HTT (0.53) CYP1A2HTTHIF1AARKMT2A
SCHEMBL22020008 0.88 HTT (0.53) CYP1A2HTTHIF1AARKMT2A
SCHEMBL20610370 0.88 HTT (0.53) CYP1A2HTTHIF1AARKMT2A
SCHEMBL11967041 0.88 HTT (0.53) CYP1A2HTTHIF1AARKMT2A
SCHEMBL15349 0.88 HTT (0.53) CYP1A2HTTHIF1AARKMT2A
SCHEMBL3774134 0.86 KMT2A (0.53) HTTHIF1AARKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090301346-A1 DENTAL RESIN-BASED CEMENT COMPOSITION KABUSHIKI KAISHA SHOFU (JP) 2009-12-10 US disclosed