Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988091 | 0.78 | PTPN1 (0.49) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL29503118 | 0.75 | HPGD (0.63) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL1121822 | 0.73 | HPGD (0.60) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL22775116 | 0.73 | HPGD (0.56) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL19141211 | 0.73 | RAB7A (0.39) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL1857150 | 0.71 | TP53 (0.38) | HPGDSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL31564016 | 0.69 | ALDH1A1 (0.40) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL31564047 | 0.66 | MAPT (0.35) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL524621 | 0.66 | CYP1A2 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3804422 | 0.66 | CYP1A2 (0.44) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124086-A2 | ANTIBACTERIAL DRUG FOR TREATMENT OF STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIAL INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2009-10-08 | — | — | WO | claimed |