Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 6/20 | 0.34 |
| ▸ | RARG | P13631 | 6/20 | 0.34 |
| ▸ | RARA | P10276 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 8/20 | 0.34 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028813 | 0.79 | RARB (0.38) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL3300808 | 0.72 | RARB (0.56) | ALKRARBRARGRARACYP3A4 | |
| SCHEMBL995907 | 0.72 | CYP3A4 (0.70) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL3765859 | 0.66 | MEN1 (0.37) | KMT2A | |
| SCHEMBL12391039 | 0.64 | ASIC3 (0.50) | RARBRARGMAP3K14L3MBTL1KMT2A | |
| SCHEMBL12617402 | 0.64 | ALK (0.38) | ALKMAP3K14BACE1KCNH2ALDH2 | |
| SCHEMBL5419989 | 0.64 | RARB (0.36) | ALKRARBRARGRARACYP3A4 | |
| SCHEMBL12479426 | 0.64 | ALDH1A1 (0.57) | MAP3K14 | |
| SCHEMBL14949230 | 0.63 | PIKFYVE (0.45) | MAP3K14L3MBTL1PIK3CDPIK3R1KMT2A | |
| SCHEMBL13768258 | 0.63 | TTBK1 (0.43) | ALKCYP3A4MAP3K14L3MBTL1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015107542-A2 | TAZAROTENE WITH LOW DIMER IMPURITY FOR TREATING ACNE OR PSORIASIS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2015-07-23 | — | — | WO | disclosed |
| WO-2009116075-A2 | PROCESS FOR PREPARATION OF TAZAROTENE | INDOCO REMEDIES LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |