Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.76 |
| ▸ | ITGAV | P06756 | 20/20 | 0.76 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370498 | 1.00 | ITGB3 (0.76) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL3884027 | 0.90 | ITGB3 (0.76) | ITGB3ITGAVITGB5 | |
| SCHEMBL7944250 | 0.86 | ITGAV (0.82) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL7944256 | 0.86 | ITGAV (0.82) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL3885042 | 0.86 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL3885043 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL3886509 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL3885035 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL3893571 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL4371981 | 0.84 | ITGAV (0.64) | ITGB3ITGAVITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | claimed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | claimed |
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |