Biotin

Biotin

SCHEMBL437052

O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.O=C1CCC(=O)N1O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.81
MEN1 O00255 1/20 0.81
ABL1 P00519 1/20 0.81
LMNA P02545 1/20 0.81
PKM P14618 1/20 0.81
IDE P14735 1/20 0.81
MAPK1 P28482 1/20 0.81
KMT2A Q03164 1/20 0.81
RIN1 Q13671 1/20 0.81
L3MBTL1 Q9Y468 1/20 0.81
HLCS P50747 6/20 0.57
CA12 O43570 7/20 0.49
CA1 P00915 7/20 0.49
CA2 P00918 7/20 0.49
CA9 Q16790 7/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL486785 1.00 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL395991 0.99 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL28043225 0.96 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23002817 0.94 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9497602 0.91 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 0.90 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9841217 0.90 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 0.90 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 0.90 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL410686 0.90 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118275697-A Immunochromatography test strip for detecting hypersensitive myocardial troponin T and preparation method and application thereof 广东省大湾区华南理工大学聚集诱导发光高等研究院 2024-07-02 CN claimed
CN-118275698-A Myocardial troponin I immunochromatography detection card, kit and application thereof 广东省大湾区华南理工大学聚集诱导发光高等研究院 2024-07-02 CN claimed
CN-118275696-A Aggregation-induced emission immunochromatography test strip for detecting growth differentiation factor-15 and preparation method and application thereof 广东省大湾区华南理工大学聚集诱导发光高等研究院 2024-07-02 CN claimed
CN-117092344-B Kit for detecting staphylococcus aureus protein A and application thereof 武汉睿奇生物工程有限公司 2024-04-19 CN claimed
US-20230341388-A1 METHOD FOR MANUFACTURING TEST STRIP FOR MULTIPLEX IMMUNOASSAY ANALYSIS, AND TEST STRIP MANUFACTURED USING SAME PRECISION BIOSENSOR INC. (KR) 2023-10-26 US claimed
CN-109738630-B High-sensitivity magnetic bead sorting combined colloidal gold marked exosome immune electron microscope method 复旦大学附属华山医院 2023-08-22 CN claimed
WO-2023149585-A1 CELL LABELLING METHOD 国立研究開発法人理化学研究所 2023-08-10 WO claimed
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 EP claimed
CN-114989299-B Composition of monoclonal antibody, application of composition, reagent, kit and method for detecting human interleukin 1 beta 北京索莱宝科技有限公司 2023-05-26 CN claimed
CN-115343482-A Tau protein (TAU) detection kit and preparation method thereof 宁波海尔施智造有限公司 2022-11-15 CN claimed
US-7622277-B2 suitable as carriers for drugs used for the treatment of diseases of the central nervous system; can penetrate the blood-brain barrier MASSEY UNIVERSITY (NZ) 2009-11-24 US claimed
CN-1229645-C Method of labeling biomolecular by CdTe Nano crystal coupled to fluorescence of strepto affinant UNIV JILIN (CN) 2005-11-30 CN claimed
CN-1540349-A Method of labeling biomolecular by CdTe Nano crystal coupled to fluorescence of strepto affinant 吉林大学 2004-10-27 CN claimed
EP-0627939-B1 CONJUGATES OF BIOTIN AND DEFEROXAMINE FOR RADIOIMMUNOIMAGING AND RADIOIMMUNOTHERAPY UNIV ROCHESTER (US) 1997-12-03 EP claimed
US-5567811-A Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides AMERSHAM INTERNATIONAL PLC (GB) 1996-10-22 US claimed
EP-0527184-B1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES AMERSHAM INT PLC (GB) 1995-08-02 EP claimed
EP-0589004-A1 PROCESS FOR THE DETERMINATION OF PEPTIDES CORRESPONDING TO IMMUNOLOGICALLY IMPORTANT EPITOPES AND THEIR USE IN A PROCESS FOR DETERMINATION OF ANTIBODIES OR BIOTINYLATED PEPTIDES CORRESPONDING TO IMMUNOLOGICALLY IMPORTANT EPITOPES, A PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM N.V. INNOGENETICS S.A. (BE) 1994-03-30 EP claimed
WO-1993018054-A2 PROCESS FOR THE DETERMINATION OF PEPTIDES CORRESPONDING TO IMMUNOLOGICALLY IMPORTANT EPITOPES AND THEIR USE IN A PROCESS FOR DETERMINATION OF ANTIBODIES OR BIOTINYLATED PEPTIDES CORRESPONDING TO IMMUNOLOGICALLY IMPORTANT EPITOPES, A PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM N.V. INNOGENETICS S.A. (BE) 1993-09-16 WO claimed
EP-0527184-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES. AMERSHAM INT PLC (GB) 1993-02-17 EP claimed
WO-1991017169-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES AMERSHAM INTERNATIONAL PLC (GB) 1991-11-14 WO claimed