Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373598 | 0.85 | ALDH1A1 (0.57) | ALDH1A1CYP3A4L3MBTL1GAAHTT | |
| SCHEMBL2374034 | 0.81 | TSHR (0.52) | ALDH1A1CYP3A4POLBL3MBTL1TDP1 | |
| SCHEMBL1291738 | 0.79 | GAA (0.56) | ALDH1A1CYP3A4GAAHTTTDP1 | |
| SCHEMBL3103960 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CYP3A4GAAHTTTDP1 | |
| SCHEMBL1401378 | 0.79 | HTT (0.49) | ALDH1A1CYP3A4POLBL3MBTL1HTT | |
| SCHEMBL28016967 | 0.79 | POLB (0.58) | ALDH1A1CYP3A4POLBL3MBTL1HTT | |
| SCHEMBL2310312 | 0.78 | CYP1A2 (0.52) | ALDH1A1CYP3A4HSD17B10TSHRCYP1A2 | |
| SCHEMBL9106099 | 0.78 | HTT (0.58) | ALDH1A1CYP3A4POLBL3MBTL1HTT | |
| SCHEMBL1455155 | 0.78 | ALDH1A1 (0.62) | ALDH1A1CYP3A4POLBTDP1MAPT | |
| SCHEMBL4370933 | 0.77 | CHEK1 (0.41) | ALDH1A1CYP3A4HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135313-A1 | HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS | 3M Innovative Properties Company (US) | 2009-12-23 | — | — | EP | claimed |
| WO-2008127828-A1 | HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-10-23 | — | — | WO | claimed |