SCHEMBL2373598

SCHEMBL2373598

COc1cc([N+](=O)[O-])c(Cl)cc1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 2/20 0.57
GAA P10253 1/20 0.56
HTT P42858 1/20 0.53
TDP1 Q9NUW8 2/20 0.51
MAPT P10636 3/20 0.47
KDM4E B2RXH2 2/20 0.47
ALOX15 P16050 1/20 0.47
PRKDC P78527 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 2/20 0.47
NPC1 O15118 1/20 0.43
MAPK1 P28482 3/20 0.42
RAF1 P04049 1/20 0.42
HPGD P15428 1/20 0.42
GFER P55789 1/20 0.42
PAX8 Q06710 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3103960 0.93 ALDH1A1 (0.53) ALDH1A1CYP3A4GAAHTTTDP1
SCHEMBL1291738 0.86 GAA (0.56) ALDH1A1CYP3A4GAAHTTTDP1
SCHEMBL3103536 0.85 LMNA (0.59) ALDH1A1CYP3A4HTTTDP1MAPT
SCHEMBL10020888 0.85 HTT (0.59) ALDH1A1CYP3A4GAAHTTTDP1
SCHEMBL4370930 0.85 ALDH1A1 (0.43) ALDH1A1CYP3A4GAAHTTTDP1
SCHEMBL9106099 0.84 HTT (0.58) ALDH1A1CYP3A4HTTTDP1MAPT
SCHEMBL10814747 0.84 ALDH1A1 (0.51) ALDH1A1CYP3A4HTTTDP1MAPT
SCHEMBL4799531 0.84 HTT (0.58) ALDH1A1CYP3A4GAAHTTTDP1
SCHEMBL6815710 0.84 HTT (0.58) ALDH1A1CYP3A4GAAHTTTDP1
SCHEMBL23110719 0.82 ALDH1A1 (0.53) ALDH1A1CYP3A4MAPTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287568-B2 High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-15 US claimed
US-20110319257-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
EP-2135313-B1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES CO (US) 2011-09-14 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
JP-2218650-A None JP disclosed
US-20240408093-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. 2024-12-12 US disclosed
WO-2018060072-A1 NEW SUBSTITUTED BENZIMIDAZOLES, METHODS FOR THE PRODUCTION OF SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAME, AND USE OF SAME TO PRODUCE DRUGS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-04-05 WO disclosed
WO-2018060174-A1 SUBSTITUTED BENZIMIDAZOLES, PHARMACEUTICAL PREPARATIONS CONTAINING SAME, AND USE OF SAME TO PRODUCE DRUGS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-04-05 WO disclosed
US-9287568-B2 High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-15 US disclosed
US-20110319257-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US disclosed
EP-2135313-B1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES CO (US) 2011-09-14 EP disclosed
EP-2135313-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M Innovative Properties Company (US) 2009-12-23 EP disclosed
US-4132786-A ANTIEMETICS, ANTICONVULSANTS, ANESTHETICS, ANTIBIOTICS MOREAU ROBERT C 1979-01-02 US disclosed
US-4096157-A PIGMENTS HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed
US-4083845-A DYEING CELLULOSE FIBER BAYER AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4079052-A Diazopigments containing pyridine derivatives CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed
US-4052374-A UNSYMMETRICAL 1:2-CHROMIUM COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3957860-A SULFAMIC ACID CIBA-GEIGY AG (CH) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240408093-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE FGFR3, FGFR1, ERBB3 ALDH1A1 4423/4885CYP3A4 2811/4885GAA 3195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.