SCHEMBL437108

SCHEMBL437108

O=C(O)C1=CC=C(c2ccc(C(=O)O)cc2)CC1(C(=O)O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
CA1 P00915 4/20 0.37
CA2 P00918 3/20 0.37
SRD5A2 P31213 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
POLB P06746 2/20 0.35
BLM P54132 1/20 0.35
GRM1 Q13255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28492399 0.82 TSHR (0.40) TSHRTP53RXRARXRBBCL2L1
SCHEMBL4454498 0.81 TP53 (0.39) TSHRTP53RXRARXRBBCL2L1
SCHEMBL9617659 0.81 RARB (0.42) TSHRTP53RXRARXRB
SCHEMBL261720 0.77 SRD5A2 (0.44) TSHRTP53RXRARXRBCA1
SCHEMBL30359384 0.77 RXRA (0.40) TSHRTP53RXRARXRBBCL2L1
SCHEMBL8339417 0.73 RXRA (0.41) TSHRTP53RXRARXRBCA1
SCHEMBL8101256 0.72 TDP1 (0.32) TP53ALDH1A1KDM4EMAPTPOLB
Hydrochloric Acid SCHEMBL11043882 0.71 TDP1 (0.31) TP53ALDH1A1KDM4EMAPTPOLB
SCHEMBL18663392 0.70 SMN1; SMN2 (0.36) BCL2L1CA1CA2MAPTMEN1
SCHEMBL17342672 0.67 TSHR (0.46) TSHRTP53RXRARXRBBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763436-A Polyimide film with low dielectric loss 达迈科技股份有限公司 2022-07-19 CN claimed
CN-113871723-A Solid electrolyte and preparation method thereof 佛山(华南)新材料研究院 2021-12-31 CN claimed
EP-3856510-A1 HIGH-TEMPERATURE POLYMER AEROGEL COMPOSITES Aerogel Technologies, LLC (US) 2021-08-04 EP claimed
WO-2020069023-A1 HIGH-TEMPERATURE POLYMER AEROGEL COMPOSITES AEROGEL TECHNOLOGIES, LLC (US) 2020-04-02 WO claimed
WO-2016195692-A1 POROUS PROPPANTS HALLIBURTON ENERGY SERVICES, INC. (US) 2016-12-08 WO claimed
US-9221954-B2 Polyimide film KOLON INDUSTRIES, INC. (KR) 2015-12-29 US claimed
US-8974903-B2 Porous cross-linked polyimide-urea networks OHIO AEROSPACE INSTITUTE (US) 2015-03-10 US claimed
US-20150025200-A1 COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-01-22 US claimed
EP-2726552-A2 POLYIMIDE-COATED FILLERS E. I. Du Pont de Nemours and Company (US) 2014-05-07 EP claimed
US-20130194814-A1 BENT LAYERED STRUCTURE AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2013-08-01 US claimed
US-20110311796-A1 POLYIMIDE FILM KOLON INDUSTRIES, INC. (KR) 2011-12-22 US claimed
JP-2010536981-A 2010-12-02 JP claimed
EP-2181144-A1 POLYIMIDE FILM Kolon Industries Inc. (KR) 2010-05-05 EP claimed
WO-2009025479-A1 POLYIMIDE FILM KOLON INDUSTRIES, INC. (KR) 2009-02-26 WO claimed
US-20050107526-A1 Polyimide precursor solution, transfer/fixing member and process for producing polyimide seamless belt SUZUKA FUJI XEROX CO., LTD (JP) 2005-05-19 US claimed
US-6706346-B2 COMPRESSION MOLDING, CALCINING, THEN VACUUM ENCAPSULATING TO FORM MOLDED BODIES EXHIBITING HIGH MOISTURE ABSORPTION, LOW CHEMICAL RESISTANCE AND DIMENSIONAL STABILITY; MECHANICAL STRENGTH UBE INDUSTRIES, LTD. (JP) 2004-03-16 US claimed
US-20020037995-A1 Process for production of polyimide molded bodies and polyimide molded bodies UBE INDUSTRIES, LTD. 2002-03-28 US claimed
US-20020030299-A1 Process for production of polyimide molded bodies and polyimide molded bodies UBE INDUSTRIES, LTD. 2002-03-14 US claimed
US-20020019081-A1 Process for fabricating thin film transistors E INK CORPORATION 2002-02-14 US claimed
US-6048959-A POLYETHERIMIDE COPOLYMERS AND FORMING THIN FILMS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2000-04-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025200-A1 COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE DDT, DTD1, DRD1 TSHR 2891/4885TP53 3397/4885RXRA 2970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.