SCHEMBL8101256

SCHEMBL8101256

NC1=CC=C(c2ccc(N)cc2)CC1(C(=O)O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.32
CYP3A4 P08684 2/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
ALPL P05186 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
MITF O75030 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
NFKB1 P19838 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
GFER P55789 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11043882 0.98 TDP1 (0.31) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
SCHEMBL9579523 0.83 CYP3A4 (0.35) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
Hydrogen Peroxide SCHEMBL3706944 0.77 CYP3A4 (0.36) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
SCHEMBL29104505 0.75 CYP3A4 (0.37) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
SCHEMBL2697748 0.75 CYP3A4 (0.37) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
SCHEMBL41543 0.73 CYP3A4 (0.39) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
SCHEMBL28702961 0.72 CYP3A4 (0.34) TDP1CYP3A4TAAR1HSD17B10ALDH1A1
SCHEMBL914860 0.72 ALDH1A1 (0.36) TDP1CYP3A4ALDH1A1TP53MAPT
SCHEMBL27713777 0.72 ALDH1A1 (0.36) TDP1CYP3A4ALDH1A1TP53
SCHEMBL437108 0.72 TSHR (0.39) TDP1ALDH1A1TP53KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739169-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS Massachusetts Institute Of Technology (US) 2014-06-11 EP claimed
WO-2013019865-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
WO-2024013492-A1 HYDROGEN SULFIDE SCAVENGING COMPOSITIONS SWELLFIX UK LIMITED (GB) 2024-01-18 WO disclosed
CN-115840335-A Negative photosensitive polyimide composition, method for producing pattern, cured product, and electronic component 江苏艾森半导体材料股份有限公司 2023-03-24 CN disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
CN-107011924-B Photoalignment materials with side substitution 罗利克有限公司 2021-06-01 CN disclosed
WO-2021003162-A2 FRUSTRATED LEWIS PAIR-IMPREGNATED POROUS MATERIALS AND USES THEREOF UNIVERSITY OF SOUTH FLORIDA (US) 2021-01-07 WO disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
WO-2019193854-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL ELEMENT, AND PRODUCTION METHOD FOR LIQUID CRYSTAL ELEMENT JSR株式会社 2019-10-10 WO disclosed
WO-2019193855-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL ELEMENT, AND PRODUCTION METHOD FOR LIQUID CRYSTAL ELEMENT JSR株式会社 2019-10-10 WO disclosed
CN-108693702-A Hardening resin composition, laminate structure, its solidfied material and electronic unit 太阳油墨制造株式会社 2018-10-23 CN disclosed
EP-0792257-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1997-09-03 EP disclosed
EP-0287909-B1 AMYLOIDOSIS AND ALZHEIMER'S DISEASE DIAGNOSTIC ASSAY AND REAGENTS THEREFOR SALUTAR, INC. (US) 1992-09-02 EP disclosed
US-5039511-A Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1991-08-13 US disclosed
EP-0438382-A1 Disubstituted aromatic dianhydrides and polyimides prepared therefrom CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4933156-A Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1990-06-12 US disclosed
EP-0287909-A1 Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1988-10-26 EP disclosed
US-4467085-A CHROMOGEN BONDED TO POLYMERS Scharf, Gerhard (DE) 1984-08-21 US disclosed
EP-0039027-A1 Chemical compounds, method for their preparation, means containing these compounds and their application Scharf, Gerhard (DE) 1981-11-04 EP disclosed
US-4026876-A Soluble polyamide-imides derived from phenylindane diamines CIBA-GEIGY CORPORATION (US) 1977-05-31 US disclosed