Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057691 | 0.83 | TSHR (0.48) | HTR1ATSHRHPGDHSD11B1 | |
| SCHEMBL4057842 | 0.82 | HTR1A (0.43) | HTR1ATSHRHPGDHSD11B1 | |
| SCHEMBL13690407 | 0.81 | ATR (0.43) | HTR1ATSHR | |
| SCHEMBL4062791 | 0.81 | HTR1A (0.44) | UBE2MDCUN1D1HTR1ATSHR | |
| SCHEMBL4048819 | 0.79 | GPR119 (0.40) | — | |
| SCHEMBL4053675 | 0.79 | CYP2C19 (0.37) | TSHR | |
| SCHEMBL13690522 | 0.78 | ATR (0.42) | HTR1ATSHR | |
| SCHEMBL4050804 | 0.78 | HTR1A (0.41) | HTR1ATSHR | |
| SCHEMBL13690548 | 0.78 | JAK2 (0.44) | HTR1ATSHRHSD11B1 | |
| SCHEMBL13690362 | 0.77 | GPR119 (0.41) | HTR1ATSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |